Dr. Rakesh K. Singh

Associate Professor
Ph. D. (BHU)
Contact Information:

Department of Biochemistry, Institute of Science

Cellular: �+ 91-9415615185

E-Mail: [email protected], [email protected]

Employer Web: www.bhu.ac.in/biochemistry/rks.html

http://scholar.google.co.in/citations?user=INNQjMIAAAAJ&hl=en

 

 

 

 

Academic Qualifications

 

S/N

Degree

Institution

Year

1.

B.Sc. (Biology)

University of Gorakhpur, Gorakhpur

1994

2.

M.Sc.(Biochemistry)

Dr. RML Avadh University, Faizabad

1997

3.

Ph.D. (Biochemistry)

Banaras Hindu University, Varanasi

2002

 

Research Area

Immuno-biology of human diseases: Currently we are working on T cells, β cells, fibroblasts, macrophages biology in infectious and non-infectious diseases. Our major interest is to identify host and parasitic factors to induce multi-functionality of immune cells towards a better vaccine induced response.

Research Projects

 

S.N

Title

Duration & Fund Received

Funded by

1.

Delineation of miRNAs role in macrophage dysfunction during L. donovani infection.

Dec, 2013 � Dec, 2016,

Principle Investigator

Cost: 53.59 Lakhs (apr.)

Department of Science and Technology, New Delhi.

2.

Identification of Leishmanial antigens modulating NRAMP1 iron efflux pump function.

Sep, 2009 � March, 2013, Principle Investigator,� Cost: 50 Lakhs (apr.)

Department of Biotechnology, New Delhi.

3.

Discovery of leishmanial excretory-secretory antigens (LESAs) linked to macrophage dysfunction.

Jan, 2009 � Jan, 2012, Principle Investigator.

Cost: 7 Lakhs (apr.)

Council of Science and Technology, State of Uttar Pradesh, Lucknow, UP, India.

4.

A study on the diagnostic and prophylactic potentials of urinary leishmanial proteins (ULPs).

Jun, 2008 � May, 2011, Principle Investigator,

Cost: 17 Lakhs (apr.)

Council of Scientific and Industrial Research, New Delhi, India.

5.

Identification of toll-like receptor related antigens in Leishmania donovani.

Jun, 2008 � May, 2011, Principle Investigator.

Cost: 17 Lakhs (apr.)

Department of Science and Technology, New Delhi, India.

6.

Field evaluation of novel diagnostic tests for visceral leishmaniasis: Freeze dried DAT, rK39 and rK26 dipstick and KATEX (latex agglutination urine test).

Jan, 2004 � Dec, 2005, Co-Principle Investigator.

Tropical Diseases Research, World Health Organization, Geneva.

Honors/Awards/Fellowships (National/ International)

IUSSTF Fellow, 2013; Indo US Science and Technology Forum, New Delhi

Young Scientist Award and Grant (2009); Council of Science and Technology, Government of Uttar Pradesh, India

Young Scientist Award and� Grant (2008); Department of Science and Technology, Ministry Human Resource, Government of India

EGIDE Fellow, 2004-5, Campus France, New Delhi

Research (Ph.D./PDF) Guidance

Ph. D. Awarded: 07, Working: 04

PDF: 03

S/N

Candidate name

Thesis title

Award Year

Post Ph.D. Placements

1.

Dr. (Ms) Surabhi Bajpai

An in vivo and in vitro study on connexins, the gap junction protein in diabetic wound healing.

2012

DST Inspire Faculty, (Asst. Professor Eq.), BSBE, IIT, Kanpur, India.

2.

Dr. (Ms) Ankita Srivastava

A study on leishmanial antigens linked to protective immune response against visceral Leishmaniasis.

2012

DS Kothari PDF, University of Lucknow, India.

3.

Dr. Neeraj Dwivedi

QTL mapping of morphological and biological traits in Capsicum annum �L.

2012

PDF (DST young Scientist, TERI, New Delhi, India).

4.

Dr. Jalaj Kumar Gour

Studies on leishmanial excretory secretory antigens.

2012

Asst. Professor, Department of Biochemistry, Allahabad Central University, India.

5.

Dr. Vinod Kumar

A study on leishmanial urinary proteins and their immunogenic properties.

2013

Dept. of Biotechnology Research Associateship, under Dr. Pradeep Das, RMRI, ICMR, Patna.

6.

Dr. (Ms) Nisha Singh

Studies on the role of natural resistance associated macrophage protein 1 (NRAMP1) in visceral Leishmaniasis.

2014

Asst. Professor, Dept. of Biochemistry, HNB University, Srinagar, Uttarakhand.

 

7.

Mr. Mallikarjuna Rao Gedda

A study on fibroblasts dysfunction in diabetic wounds.

2017 (submitted)

NA

8.

Mr. Neeraj Tiwari

Delineation of immune modulatory mechanisms during host parasite interaction.

Working

NA

 

9.

Mr. Ashish K. Singh

A study on bacterial biofilms.

Working

NA

10.

Ms. Kavita Paul

Studies on vaccine induced responses in parasitic diseases

Working

NA

11.

Mr. Rajan Singh

Delineating the role of immune inhibition on T cells function

Working

NA

10.

PDF (DSK-PDF)

1.      Dr. Manish Mishra* (Completed)

2.      Dr. Arun Kumar Rawat (Working)

3.      Dr. Ashish Kumar (Awarded)

*Associate Professor

Biochemistry & Genetics

All Saints University, Kingstown.

List of 10 major Publications

1.      Tiwari N, Kumar V, Gedda MR, Singh A, Singh SP, Singh RK* (2017). Identification and characterization of miRNAs in response to Leishmania donovani infection: delineation of their roles in macrophage dysfunction. Frontier in Microbiology. DOI.org/10.3389/fmicb.2017.00314.

2.      Sreenivas G, Ismail N, Singh RK, Nakhasi HL. Modulation of innate immune mechanisms to enhance vaccine induced immunity: Role of co-inhibitory molecules. Frontiers in Immunology, 2016: 7, 187, doi: 10.3389/fimmu.2016.00187.

3.      Singh N, Mishra BB, Bajpai S, Tiwari VK*, Singh RK*. Natural Product based Leads to Fight against Leishmaniasis. Bioorganic Medicinal Chemistry, 2014; 22: 18-45.

4.      Singh N, Bajpai S, Kumar V, Gour JK and Singh RK*. Identification and functional characterization of Leishmania donovani secretory peroxidase: Delineating its role in NRAMP1 expression and function. PLoS One 2013; 8 (1): e53442.

5.      Singh N, Kumar M, and Singh RK*. Leishmaniasis: Current status of available drugs and new potential drug targets. Asian Pacific Journal of Tropical Medicine, 2012; 5(6): 485-497.

6.      Kumar H, Mishra M, Bajpai S, Pokharia D, Arya A K, Singh RK, Tripathi K. Correlation of insulin resistance, beta cell function and insulin sensitivity with serum sFas and sFasL in newly diagnosed type 2 diabetes. Acta Diabetologica, 2011: 50; 511-518.

7.      Bajpai S, Mishra M, Kumar H, Tripathi K, Singh RK*. Effect of different antidiabetic drugs on diabetic wound healing via regulation of connexins and oxidative stress markers. Diabetes 2011; 60 (suppl.1): A289. [A]

8.      Sundar S, Singh RK, Bimal S. K, Gidwani K, Mishra A, Maurya R, Manandhar KD, Singh SK, Boelart M, and Rai M. Comparative evaluation of parasitology and serological tests in the diagnosis of visceral leishmaniasis in India. A phase III diagnostic accuracy study. Tropical Medicine and International Health, 2007; 12 (2): 284-289.

9.      Sundar S, Singh RK, Maurya R, Kumar B, Chhabra A, Singh V, Rai M. Serological diagnosis of Indian visceral leishmaniasis: direct agglutination test versus rK39 strip test. Transactions of Royal Society of Tropical Medicine and Hygiene, 2006; 100 (6): 533 - 537.

10.  Sundar S, Maurya R, Singh RK, Bharti K, Chakravarty J, Parekh A, Rai M, Kumar K, Murray HW. Rapid, noninvasive diagnosis of visceral leishmaniasis in India: comparison of two immunochromatographic strip tests for detection of anti-k39 antibody. Journal of Clinical Microbiology, 2006; 44(1): 251 - 253.

Research Publications (*corresponding author)

1.      Singh RK*, Ismail N, Gannavaram S, Nakhasi, HL (2017). Centrin deleted Leishmania donovani parasites induce CD4 T cell multifunctionality and proliferation through down regulation of CD200-CD200R immune inhibitory axis. Ready for submission.

2.      Yadav CL, Manar KK, Yadav MK, Tiwari N, Singh RK, Drew MGB, Singh N (2017). Synthesis, crystal structure and properties of new homoleptic Ni(II)Pd(II) oxodithioester chelates. Journal of Molecular Structure (submitted).

3.      Kumar R, Yadav P, Gaurav A, Gedda MR, Tiwari N, Singh RK, Tewari A (2017). Molecular Docking and In-Vitro Antileishmanial Activity of Triazole Based Propylene Bridged Heteroaromatic System. ��Medicinal Chemistry Research (submitted). [IF: 2.25]

4.      Birla H, Rai SN, Singh S, Zahra W, Rawat A, Tiwari N, Singh RK, Singh SP (2017). Neuroprotective and anti inflammatory role of Tinospora cardifolia in MPTP induced Parkinsonian mouse model. Frontier in Microbiology, (accepted, under minor revision). [IF: 4.16]

5.      Koley S, Tiwari N, Srivastava N, Singh RK, Singh MS (2017). 2-Mercaptoquinoline Analogues: A Potent Antileishmanial Agent. Bioorganic and Medicinal Chemistry Letters (accepted, under publication). [IF: 2.4]

6.      Kumar V, Kumar A, Das S, Kumar A, Kumar A, Verma S, Mandal A, Singh RK, Das P (2017). Leishmania donovani induced hypoxia inducible factor-alpha regulates miR-210 and NF-κB for survival in macrophages. Frontier in Microbiology, (accepted, under minor revision). [IF: 4.16]

7.      Tiwari N, Kumar D, Bajpai S, Singh RK* (2017). Challenges of visceral leishmaniasis in Indian subcontinent: an immunological viewpoint on asymptomatic infections, sterile cure and post kala azar dermal leishmaniasis. Asian Pacific J of Tropical Medicine (accepted, under publication). [IF: 0.95]

8.      Singh A, Prakash P*, Singh R, Nady N, Firdaus Z, Pandey A, Bansal M, Singh RK, Srivastava A, Roy JK, Mishra M, and �Singh RK* (2017). Curcumin Quantum dots mediated degradation of bacterial biofilms. Frontier in Microbiology, https://doi.org/10.3389/fmicb.2017.01517. [IF: 4.16]

9.      Singh AK, Prakash P, Achra A, Singh GP, Das A, Singh RK. Standardization and classification of in vitro biofilm formation by clinical isolates of staphylococcus aureus.�������� J. Global Infectious Diseases 2017; 9(3): 93-101.

10.  Mishra SK, Tripathi G, Kishore N, Singh RK, Tripathi VK. Drug development against tuberculosis: impact of alkaloids. European Journal of Medicinal Chemistry 2017; DOI: 10.1016/j.ejmech.2017.06.005. [IF: 3.9]

11.  Kumar V, Tiwari N, Gedda M, Singh RK*. Leishmania donovani infection activates TLR 2, 4 expressions and TGF-β mediated apoptosis in renal tissues. Braz. J. Infect. Dis. 2017; 10.1016/j.bjid.2017.04.007. [IF: 1.4]

12.  Tiwari N, Gedda MR, Tiwari VK, Singh SP, Singh RK*. Limitations of current therapeutic options, possible drug targets and scope of natural products in control of leishmaniasis. Mini Review in Medicinal Chemistry 2017; DOI: 10.2174/1389557517666170425105129. [IF: 2.84]

13.  Manar K, Yadav C, Tiwari N, Singh RK, Mishra R, Yadav A, Drew M, and Singh N. Effect of functionalities on the crystal structures of new zinc (II) dithiocarbamates: A combined anti-leishmanial and thermal decomposition study. CrystEngComm.2017; DOI: 10.1039/C7CE00211D. [IF: 3.84]

14.  Tiwari N, Kumar V, Gedda MR, Singh A, Singh SP, Gannavaram S, Singh RK*. Identification and characterization of miRNAs in response to Leishmania donovani infection: delineation of their roles in macrophage dysfunction. Frontier in Microbiology, 2017; DOI.org/10.3389/fmicb.2017.00314. [IF: 4.16]

15.  Singh N, Gedda MR, Tiwari N, Bajpai S, Singh SP, Singh RK* (2016). Slc11a1 activation efficiently inhibits Leishmania donovani survival in host macrophages. J. Parasitic Diseases, 2016; DOI: 10.1007/s12639-016-0864-4. [IF: NA, Elsevier, PubMed listed]

16.  Sreenivas G, Ismail N, Singh RK, Nakhasi HL. Modulation of innate immune mechanisms to enhance vaccine induced immunity: Role of co-inhibitory molecules. Frontiers in Immunology, 2016; 7, 187, doi: 10.3389/fimmu.2016.00187. [IF: 5.6]

17.  Yadav MK, Rajput G, Srivastava K, Singh RK, Mishra R, Drew M, and Singh N. Anti-leishmanial activity of Ni(II), Pd(II) and  Pt(II) β-oxodithioester complexes. New Journal of Chemistry 2015; doi:10.1039/C5NJ00765H. [IF: 3.27]

18.  Dwivedi P, Mishra KB, Mishra BB, Singh N, Singh RK, and Tiwari VK. Click Inspired Synthesis of Antileishmanial Triazolyl O-Benzylquercetin Glycoconjugates. Glycoconjugate Journal 2015; 32; 127-40.� [IF: 1.828]

19.  Srivastava A, Singh RK and Chandra D. Homology model of Leishmania donovani: Udp-galactopyranose mutase binds antifungal compounds in silico. Int J Res Appl Sci Engg Techol 2015; 3; 523-531 (ISSN number 2321-9653). [IF: NA]

20.  Singh N, Mishra BB, Bajpai S, Tiwari VK*, Singh RK*. Natural Product based Leads to Fight against Leishmaniasis. Bioorganic Medicinal Chemistry, 2014; 22: 18-45. [IF: 2.793]

21.  Singh A, Bajpai S, Singh N, Kumar V, Gour JK. Singh PK and Singh RK*. Wound healing activity of standardized extract of Curculigo orchioides in streptozotocin-induced diabetic mice. Asian Pac J Trop Biomed 2014; 4(1): S48-S53. [IF: NA, Elsevier, ISSN 2221-1691, PubMed listed]

22.  Singh N, Bajpai S, Kumar V, Gour JK and Singh RK*. Identification and functional characterization of Leishmania donovani secretory peroxidase: Delineating its role in NRAMP1 expression and function. PLoS One 2013; 8 (1): e53442. [IF: 3.05]

23.  Kumar V, Gour VK, Srivastava A, Singh N, Bajpai S and Singh RK*. Leishmania donovani specific 25 and 28 kDa urinary proteins activate macrophage effector functions, lymphocyte proliferation and Th1 cytokines production. Parasitology Research 2013; 112 (4): 1427-35. [IF: 2.027]

24.  Singh S, Rajput SK, Singh M, Mishra PK, Mohan G, Kumar M, Singh RK and Gambhir IS. P53 gene: mutation and immunohistochemical analysis in patients with invasive ductal carcinoma of breast among middle north eastern Indian population. American Journal of Biochemistry and Biotechnology, 2013; 9 (4): 398-406. [IF: 0.73]

25.  Singh S, Jamal F, Mehrotra S and Singh RK. Hepatoprotective role of curcumin against acetaminophen induced toxicity in rats. International Research Journal of Biological Sciences, 2013; 2(11): 1-6. [IF: NA, ISSN 2278-3202]

26.  Dwivedi N, Kumar R, Paliwal R, Kumar U, Kumar S, Singh M, and Singh RK. QTL mapping for important horticultural traits in pepper (Capsicum annuum L.). Journal of Plant Biochemistry and Biotechnology, 2013; DOI 10.1007/s13562-013-0247-1. [IF: 1.352]

27.  Kumar M, Tripathi MK, Srivastava A, Gour JK, Singh RK, Tilak R and Asthana RK. Cyanobacteria, Lyngbya aestuarii and Aphanothece bullosa as antifungal and antileishmanial drug resources. Asian Pac J Trop Biomed, 2013: 3(6): 458-463. [IF: NA, Elsevier, PubMed listed, ISSN 2221-1691]

28.  Gour JK, Kumar V, Singh N, Bajpai S, Pandey HP, Singh RK*. Identification of Th1-responsive leishmanial excretory-secretory antigens (LESAs). Experimental Parasitology, 2012; 132: 355-361. [IF: 1. 789]

29.  Singh S, Agrawal R, Mehrotra S, and Singh RK. Effect of tert-butyl hydroperoxid (t-BHP) on Ca++ ATPase activity in rat hepatocytes and its reversal by antioxidants. Journal of Environmental Biology, 2012; 33 (5): 867-870. [IF: 0.56]

30.  Mishra BB, Gour JK, Kishore N, Tripathi VJ, Tiwari VK, Kumar V, Singh RK*. An anti-Leishmanial Prenyloxy-naphthoquinone from Roots of Plumbago zeylanica. Natural Product Research, 2012; http://dx.doi.org/10.1080/14786419.2012.696254. [IF: 1.05]

31.  Singh N, Kumar M, and Singh RK*. Leishmaniasis: Current status of available drugs and new potential drug targets. Asian Pacific Journal of Tropical Medicine, 2012; 5(6): 485-497. [IF: 0.84]

32.  Rajput SK, Dave VP, Rajput A, Pandey HP, Dutta TK and Singh RK*. A Column based rapid method for the simultaneous isolation of DNA, RNA, miRNA and proteins. Cell Biology International, 2012; 36(9): 779-783. [IF: 1.66]

33.  Kumar V, Mishra M, Rajput S, Bajpai S and Singh RK*. Detection of human kininogen in the urine of visceral leishmaniasis patients. Parasitological Research, 2012; 111: 1851-1855. [IF: 2.02]

34.  Srivastava A, Singh N, Mishra M, Kumar V, Gour JK, Bajpai S, Singh S, Pandey HP and Singh RK*.� Identification of toll-like receptor related Th1 responsive Leishmania donovani amastigote specific antigens. Molecular and Cellular Biochemistry, 2012; 359: 359-368. [IF: 2. 61]

35.  Singh RK*, Srivastava A, Singh N. Toll-like receptor signaling: A perspective to develop vaccine against leishmaniasis. Microbiological Research 2012; 167: 445-451. [IF: 2.56]

36.  Singh RK*, Srivastava A, Gour J and Tiwari V. Targeting Leishmania species: nanotechnological prospects. Advanced Science Letters, 2012; 5: 11-20. [IF: 1.2]

37.  Mishra M, Kumar H, Bajpai S, Singh RK, Tripathi K. Level of serum IL-12 and its correlation with endothelial dysfunction, insulin resistance, proinflammatory cytokines and lipid profile in newly diagnosed T2DM. Diabetes Research and Clinical Practice, 2011; 94: 255-261. [IF: 3.352]

38.  �Kumar H, Mishra M, Bajpai S, Pokharia D, Arya A K, Singh RK, Tripathi K. Correlation of insulin resistance, beta cell function and insulin sensitivity with serum sFas and sFasL in newly diagnosed type 2 diabetes. Acta Diabetologica, 2011; 50; 511-518. [IF: 3.07]

39.  Bajpai S, Mishra M, Kumar H, Tripathi K, Singh S K, Pandey H P, Singh RK*. Effect of selenium on connexins expression, angiogenesis and antioxidant status in diabetic wound healing. Biological Trace Element Research, 2011; 144: 327-338. [IF: 1.30]

40.  Hussain G, Singh RK, Kumar V. Anti-diabetic activity of standardized extract of Quassia amara in nicotinamide-streptozotocin-induced diabetic rats. Phytotherapy Research, 2011; 25(12): 1806-12. [IF: 2. 69]

41.  Kumar V, Gour J K, Bajpai S, Mishra M, Singh RK*. Detection of urinary antigens and their seroreactivity with serum of patients in Leishmania donovani infection. Asian Pacific Journal of Tropical Medicine, 2011; 4(5):367-370. [IF: 0.84]

42.  Kumar R, Dwivedi N, Singh RK, Kumar S, Rai VP, Singh M. A review on molecular characterization of pepper for capsaicin and oleoresin. International Journal of Plant Breeding and Genetics, 2011; 5 (2):99-110. [IF: 0.36]

43.  Singh S, Singh M, Singh RK and Gambhir IS. Tumor suprresor p53 and its prognostic value in mutation analyses in breast cancer patients. Journal of Stress Physiology and Biochemistry, 2011; 7 (3):143-151. [IF: NA, ISSN 1997-0838]

44.  Bajpai S, Mishra M, Kumar H, Tripathi K, Singh RK*. Effect of different antidiabetic drugs on diabetic wound healing via regulation of connexins and oxidative stress markers. Diabetes 2011; 60 (suppl.1): A289. [A] [IF: 8.78]

45.  Bajpai S, Mishra M, Kumar H, Tripathi K, Singh SK, Pandey HP, and Singh RK*. Comparative Evaluation of Connexins Expression in Diabetic and Nondiabetic wounds. Digest Journal of Nanomaterials and Biostructures, 2010; 5(3):757-762. [IF: 0.756]

46.  Mishra M, Kumar H, Pokhariya D, Kumar A, Bajpai S, Singh RK, and Tripathi K. PAR-γ agonists Vs glipizide: A comparative evaluation on markers of endothelial dysfunction and angiogenesis in north Indian type 2 diabetes mellitus with cardiovascular complications. World Heart Journal, 2010; 2(2):111-118. [IF: NA, Nova, PubMed listed]

47.  Mishra M, Kumar H, Pokharia D, Arya A K, Bajpai B, Singh RK, and Tripathi K. Comparative study of IL-12p70 in controlled and uncontrolled type 2 diabetes. Diabetes, 2010; 59 (Suppl.1): A581-582. [A] [IF: 8.78]

48.  Kumar H, Mishra M, Pokharia D, Arya AK, Bajpai S, Singh SK, Singh RK and Tripathi K. sFas-L correlates negatively with insulin resistance in T2D M. Diabetes, 2010; 59 (Suppl.1):A 651. [A] [IF: 8.78]

49.  Gour JK, Srivastava A, Kumar V, Bajpai S, Kumar H, Mishra M, and Singh RK*. Nanomedicine and leishmaniasis: future prospects. Digest Journal of Nanomaterials and Biostructures, 2009; 4(3):495-499. [IF: 0.756]

50.  Bajpai S, Shukla VK, Tripathi K, Srikrishna S and Singh RK*. Targeting connexin 43 in diabetic wounds: future perspectives. Journal of Post Graduate Medicine, 2009; 55:143-149. [IF: 0.87]

51.  Mishra BB, Singh RK, Srivastava A, Tripathi VJ and Tiwari VK. Fighting against Leishmaniasis: Search for alkaloids as true potential anti-leishmanial agents. Mini-Reviews in Medicinal Chemistry, 2009; 9: 107-123. [IF: 2. 84]

52.  Mishra B, Kale R, Singh RK and Tiwari VK. Alkaloids: Future prospective to combat leishmaniasis. Fitoterapia, 2009; 80 (2): 81-90. [IF: 2.245]

53.  Mishra M, Kumar H, Pokhariya D, Kumar A, Bajpai S, Singh RK, Rai M and Tripathi K. Effect of pioglitazone, rosiglitazone and glipizide on Nox, TNF-a, VEGF, angiogenin in Type 2 diabetes with cardiovascular complications. Diabetes, 2009; 58(1):A131. [A] [IF: 8.78]

54.  Mishra M, Kumar H, Singh RK and Tripathi K. Diabetes and nano-materials. Digest Journal of Nanomaterials and Biostructures, 2008; 3 (3):109 -113 (online). [IF: 0.756]

55.  Hide M, Singh RK, Kumar B, Bannules AL, and Sundar S. A micro culture technique for isolating live Leishmania parasites from peripheral blood of visceral leishmaniasis patients Acta Tropica, 2007; 102(3):197-200. [IF: 2.68]

56.  Mishra BB, Yadav SB, Singh RK, Tripathi V. A Novel Flavonoid C-glycoside from Sphaeranthus indicus L. (Family Compositae), Molecules, 2007; 12: 2288-2291. [IF: 2.45]

57.  Sundar S, Singh RK, Bimal S. K, Gidwani K, Mishra A, Maurya R, Manandhar KD, Singh SK, Boelart M, and Rai M. Comparative evaluation of parasitology and serological tests in the diagnosis of visceral leishmaniasis 2007in India. A phase III diagnostic accuracy study. Tropical Medicine and International Health,; 12 (2): 284-289. [IF: 2.55]

58.  Sundar S, Singh RK, Maurya R, Kumar B, Chhabra A, Singh V, Rai M. Serological diagnosis of Indian visceral leishmaniasis: direct agglutination test versus rK39 strip test. Transactions of Royal Society of Tropical Medicine and Hygiene, 2006; 100 (6): 533 - 537. [IF: 1.9]

59.  Singh RK*, Pandey HP, and Sundar S. Visceral Leishmaniasis (Kala-azar): Challenges ahead. Indian Journal of Medical Research, 2006; 123: 331 -344. [IF: 2.06]

60.  Sundar S, Maurya R, Singh RK, Bharti K, Chakravarty J, Parekh A, Rai M, Kumar K, Murray HW. Rapid, noninvasive diagnosis of visceral leishmaniasis in India: comparison of two immunochromatographic strip tests for detection of anti-k39 antibody. Journal of Clinical Microbiology, 2006; 44(1): 251 - 253. [IF: 4.232]

61.  Maurya R, Singh RK, Kumar B, Salotra P, Rai M, Sundar S. Evaluation of PCR for diagnosis of Indian kala-azar and assessment of cure. Journal of Clinical Microbiology, 2005; 43 (7): 3038 - 3041. [IF: 4.232]

62.  Singh RK*, Pandey HP, Singh RH. Correlation of serotonin and monoamine oxidase levels with anxiety level in diarrhea-predominant irritable bowel syndrome. Indian Journal of Gastroenterology, 2003; 22 (3): 88-90. [IF: NA, Springer, PubMed listed]

63.  Singh RK*, Pandey HP, and Singh RH. Irritable Bowel Syndrome: challenges ahead. Current Science, 2003; 84 (12): 1525-1533. [IF: 0. 833]

64.  Yadav SB, Tripathi VJ, Singh RK, and Pandey HP. Flavanoids glycosides from Cuscuta reflexa stems and their antioxidant activity. Indian Drugs, 2001; 38 (2): 95-96. [IF: NA, PubMed listed]

65.  Yadav SB, Tripathi VJ, Singh RK, and Pandey HP. Antioxidant activity of Cuscuta reflexa stems. Indian Journal of Pharmaceutical Sciences, 2000; Nov- Dec: 477-478. [IF: 0. 762]

Book Chapters

1.      Tiwari N, Kumar A, Bajpai S, Tiwari VK, Singh RK* (2018). Leishmaniasis control: limitations of current therapeutic options and prospects of natural products. (Elsevier Book Series on Neglected Tropical Diseases, under process)

2.      Mishra BB, Kishore N, Singh RK and Tiwari VK (2013) Scope of alkaloids in anti-leishmanial drug discovery and development. In Handbook of Natural Product (Ed. K.G. Ramawat, J.M. Merillon), ISBN: 978-3-642-22143-9, DOI 10.1007/978-3-642-22144-6_91, pp 1263-1299.

3.      Mishra BB, Kale RR, Prasad V, Tiwari VK and Singh RK* (2010) Scope of Natural Products in Fighting Against Leishmaniasis. In Opportunity, Challenge and Scope of Natural Products in Medicinal Chemistry, ISBN: 978-81-308-0448-4 (Ed. VK Tiwari & BB Mishra), Research Signpost Publication, India, pp 119-151. 

4.    Sundar S, Chakravarty J, Agrawal S, Singh RK, Rai M. (2005) Visceral Leishmaniasis: Diagnostic Overview. In Multidisciplinarity for Parasites, Vectors and Parasitic Diseases (Ed. Mas-Coma S). Vol 1 pp 37-50.� ISBN:   978-88-7587-143-7, Medimond International Proceeding Division, Pianoro (Bologna), Italy.

Conferences Presentations/Invited Lectures

1.      Singh RK* (2016). Host immune inhibitory mechanisms and their perspective in the vaccine induced immunity in Leishmania donovani infection. International Symposium of Genetics and Human Phenomics, May 11-13 2016, Fudan University, Shanghai, China

2.      Singh N, Kumar V, Gour JK, Singh RK* (2012). Effects of leishmanial amastigotes specific proteins on NRAMP1 expression via modulation of macrophage effector functions. 39th Annual Conference of Indian Immunological Society, Nov. 9-11, 2012, BHU, Varanasi, India.

3.      Singh RK* (2012). Evaluation of leishmanial excretory secretory proteins for their immunological properties.� 2nd International Science Congress, Dec. 8-9, 2012, Vrindavan, India. (Best oral presentation Award)

4.      Bajpai S, Mishra M, Kumar H, Tripathi K, Singh RK* (2011). Effect of different antidiabetic drugs on diabetic wound healing via regulation of connexins and oxidative stress markers. 71st ADA, San Diego, June 24-28, USA.�

5.      Mishra M, Kumar H, Bajpai S, Singh RK, Tripathi K. (2011) Serum IL-12 and endothelial dysfunction markers in newly diagnosed type 2 diabetic patients. 4th International Conference of Diabetes India, April 15-17, 2011, New Delhi.

6.      Bajpai S, Mishra M, Kumar H, Tripathi K, Singh RK*. (2011) Effect of glibenclamide and pioglitazone on connexin regulation and diabetic wound healing. 4th International Conference of Diabetes India, April 15-17, 2011, New Delhi.

7.      Bajpai B and Singh RK*. (2011). Down regulation of connexins expression accelerates the rate of diabetic wound healing after selenium administration. 98th Indian Science Congress, Jan. 3-7, SRM University, Chennai, India.

8.      Bajpai, S. and Singh RK*. (2010) A study on impending role of connexins in diabetic wound healing. International Conference on the Role of Biomolecules in Food Security and Health Improvement (ICRBFSHI) and Silver Jubilee Convention of Indian Society of Agricultural Biochemists and Alumni Meet of Biochemists. Feb.17-19: Organized by Department of Biochemistry, Faculty of Science, Banaras Hindu University, Varanasi.

9.      Kumar V, Srivastava A, Gour JK, Srikrishna S, Pandey HP, Singh RK*. (2010) Identification of urinary leishmanial antigens for their diagnostic and prognostic potentials. (ICRBFSHI), Feb.17-19: Organized by Department of Biochemistry, Faculty of Science, Banaras Hindu University, Varanasi.

10.  Pandey, HP and Singh RK* (2009). Comparison between Immunological and Molecular methods for the diagnosis of Indian Visceral Leishmaniasis. 2nd Infectious and Endemic Diseases Scientific Conference, May 15-18: Organized by National Centre for Infectious Diseases Prevention and Control, Libya.

11.  Dwivedi N, Kumar R, Singh RK, Lima JM, Singh M, Rai M. (2009) Screening and validation of molecular markers associated with pungency trait in Capsicum anuum L. International Conference on Current Trends in Biotechnology and Implication in Agriculture, February 19-21: Organized by SVP University of Agriculture and Technology, and Society of recent Development in Agriculture, Merrut, India.

12.  Srivastava A, Bajpai S, Sundar S. and Singh RK*. (2007). Diagnosis of Indian Visceral Leishmaniasis: a Comparison between Immunological and Molecular Methods. III Symposium on Current Advances in Molecular Biochemistry:Applications in Health, Environment & Agriculture Organized by Department of Biochemistry, Lucknow University, Lucknow.

13.  Yadav SB, Singh RK and Tripathi VJ (2008).� A New Sesquiterpene lactone glycoside from Sphaeranthus indicus. International Conference on Drug Discovery and Nanotechnolgy, Jan 27-28: Organized by Department of Chemistry, YM, Nanded, India.

14.  Singh RK*, Kumar B, Maurya R and Sundar S. (2005). A micro-culture technique for the isolation of Leishmania parasites from the blood of visceral leishmaniasis patients. International Training and Research in Emerging Infectious Diseases, Asian Regional Workshop, 8-11 March, 2005, Department of Biotechnology, JNU, New Delhi, India

15.  Chakravarty J, Maurya R, Singh RK, Kumar B, Rai M, Parekh A and Sundar S. (2005) Usefulness of PCR in diagnosis and prognosis of Visceral leishmaniasis. APICON, Mumbai, India.

16.  Singh RK*, Kumar B, Pandey HP and Singh RH. (2002) A Study on serotonin and monoamine oxidase and their correlation with anxiety level in Irritable bowel Syndrome. National Conference on Innovation and Prospects in Life Sciences, organized by Pt. Ravishankar Shukla University, Raipur, Chhattisgarh, India.

Invited Lectures

1.      Singh RK*. (2017) The science of nanotechnology and its applicability in human welfare. DST Inspire Programme, Nov.29 to Dec. 01, 2017: Organized by Dr. APS University, Rewa, MP.���

2.      Singh RK* (2017). CD200 and CD200R interaction: Its role in leishmanial pathogenesis and vaccine induced immunity. In 2nd National Seminar on Current Trends in Life Science. Feb.20-21, 2017, Life Science Programme, Central University of South Bihar, Patna, India.

3.      Singh RK* (2013). Diagnostic, prognostic and immunoprophylactic capabilities of 25 and 28kDa urinary leishmanial proteins. Oct. 29-31, 2013: Recent Advancement in Biochemistry and Biotechnology: Application in Health, Environment and Agriculture. Department of Biochemistry, University of Lucknow, UP, India.

4.      Singh RK* (2013). Recent advancement in diagnosis of visceral leishmaniasis. National Symposium on Biomarkers in Health and Diseases: Bench to Bed Side. July 3-4, 2013: Department of Biochemistry, SGRRIHMS, Dehradun, UP, India.

5.      Evaluation of leishmanial excretory secretory proteins for their immunological properties. 2nd International Science Congress, Dec. 8-9, 2012, Vrindavan, India.

6.      Singh RK*, Mishra BB and Tiwari VK (2011). An anti-leishmanial naphthoquinone isolated from Plumbago zeylanica roots. National Seminar on �Expanding Horizons in Chemical Sciences, October 22-23: Department of Chemistry, Dr. APS University, Rewa, MP.

7.      Singh RK*. (2010). Detection and applicability of urinary leishmanial antigens (ULAs) in the diagnosis and prognosis of visceral leishmaniasis. �International Symposium on Recent Advances in Ecology and Management of Vectors and Vector Borne Diseases�. Dec.1-3: Organized by Defence Research and Development Establishment, DRDO, Gwalior.

8.      Singh RK*. (2010) Selenium accelerates the rate of diabetic wound healing by regulating connexins gene expression. National Seminar on �Recent Trends in Chemical Sciences, May 12-13: Department of Chemistry, Dr. APS University, Rewa, MP.���

Workshop Organized

1.        Training Cum Workshop on Basic Tools and Techniques in Biotechnology (TWBTTB-2016) organized by Biotechnology Programme, Center for Biological Sciences, Central University of South Bihar, Patna (24-30th November 2016).

2.        Workshop on Protocol for Trials on Immunological Tests for Kala-Azar in India & Nepal. Sponsored by World Health Organization, Geneva. May 16th to 20th, 2005, Kala-Azar Medical Research Center, Muzaffarpur, India

Abroad Visits: USA/France/China/Nepal

Additional Information/Achievements
Personal
Date of Birth�������������� October 02, 1974, (born in; village: chilkahar, dist.: ballia, UP)
Nationality����  ���������� Indian

Passport No��������������� L3126728

Marital Status������������ Married

Positions/Employment

Teaching

Associate Professor: Teaching and Research since Nov. 21, 2005, Department of Biochemistry, Institute of Science, Banaras Hindu University, Varanasi.

Research (PDF/Visiting Scientist)

Infectious Diseases Research Laboratory, Department of Medicine, Institute of Medical Science,Banaras Hindu University, Varanasi, India: Dec, 2002 � Oct, 2005 &

Institute of Research and Development, Unit of Research 165, Genetics and Evolution of Infectious Diseases" GEMI, UMR CNRS/IRD 2724, IRD center, BP 64501, 34394, Montpellier Cedex 5, France.� (2004&2005)

Division of Emerging and Transfusion Transmitted Diseases, OBRR, CBER, Food and Drug Administration (FDA), Silver Spring, MD, USA: (2014 - 2015)

Fellowships

IUSSTF Fellow (Indo-US Science and Technology Forum, New Delhi)

Ad-hoc Reviewer

PloS Neglected Tropical Diseases, PloS One, Natural Product Report, BMC Infectious Diseases, Bioorganic Medicinal Chemistry, Pharmacognosy Research, Fitoterapia, Parasitology Report, Sci Technol, Journal of Parasitic Diseases, Bioorganic and Medicinal Chemistry Letters, Spectro Letters, Mini Reviews in Medicinal Chemistry, Biomed Res International, Brazilian Archives of Biology and Technology, Phytomedicine, CDTH etc.