Dr.Vinod Kumar Tiwari

Assistant Professor (Organic Chemistry)

Contact Information:
Department of Chemistry
Centre of Advanced Study
Banaras Hindu University
Varanasi-221005, India
Tel. +91-542-6702466(O);Mobile:+91-9451896061 Fax: +91-542-2368174
Email Id:[email protected]

Dr. Vinod K. Tiwari was born in Bihar, India in 1976. After his BSc (1996) from UP College, Varanasi and MSc (1998) from Banaras Hindu University, he worked on Carbohydrate based biodynamic agents under the guidance of Dr. R. P. Tripathi at Central Drug Research Institute, Lucknow, India since 2000 and awarded PhD from Jawaharlal Nehru University, New Delhi (2004). He has interest on Benzotriazole Methodology since 2005 through his Adjunct Postdoctoral research with Prof. A. R. Katritzky, UF, USA. He worked on ?Chemoenzymatic synthesis of Complex Carbohydrate based Molecules? as visiting post-doctoral fellow with Prof. Xi Chen at University of California, Davis, USA (2007) and then on ?'Novel Intramolecular Glycosidic Bond Formation Methodology? as visiting Scientist with Prof. Dr. Richard R. Schmidt at Universitat Konstanz, Germany (2009). He was offered a Lecturership at Bundelkhand University, Jhansi (2004-2005) before being appointed in BHU, India (2005-continued) where he started his independent research career. He has over 70 publication including 08 Patents of high national and international repute. His research received many prestigious awards mainly Dr. D. S. Bhakuni Award, Indian Chemical Society (2004); Young Investigator Prize (2004); DST Fast Track Research for Young Scientist (2005), Most Cited Paper Award (2006); Vidya Ratan Award and Gold Medal (2008), NESA Medal (2010), Dr Arvind Kumar Memorial Award (2010), UP CST Young Scientist Award (2010), Prof. R C Shah Memorial Award, Indian Science Congress (2011-12) etc. He successfully supervised for five PhD Thesis and six MSc project. At present the Group of two RA, Four PhD and two MSc students are working with dedication on different aspect of Carbohydrate Chemistry. He delivered numerous invited lectures at different university/institutes in India, USA, and Germany. He has wide experience in Editorial job for Book Review as well as Journal where recently he invited for the Editor Position for Journal .Trends Carbohydrate Res? and recently managing as a Facilitator to publish special ARKIVOC issue to honor Prof. Richard Schmidt. His ongoing research on novel synthetic methodology has been supported for grant-in-aid from DST (2005-2008), CSIR (2008-2011) and UGC, India (2009-2012).

 
Academic Qualifications and Experience:
 
Sr. Degree Institution Year
1 BSc Udai Pratap Autonomous Institution, Varanasi, India 1996
2 MSc Banaras Hindu University, India 1998
3 PhD Jawaharlal Nehru University, New Delhi, IndiaWorking Place: Central Drug Research Institute, Lucknow (2000 to 16th Feb, 2004)Mentor: Dr R P Tripathi, Scientist F, CDRI 2004
4 Lecturer Department of Chemistry, Institute of Basic Science, Bundelkhand University, India (Position Offered) 2004
4 PDF University of Florida, Gainesville, USAMentor: Prof. Alan R Katritzky, Director 2005
5 Visiting PDF University of California, Davis, CA 95616, USAMentor: Prof. Xi Chen, Professor 2007
6 Visiting Scientist Universitat Konstanz, Konstanz, GermanyMentor: Prof Richard R Schmidt, Emeritus Professor 2009
 
Area of Specialization:

Our current research is mainly focused on different aspects of Carbohydrate Chemistry including their modifications, application in chiral synthesis, carbohydrate based ligands and most important development of Carbohydrate-containing molecules of medicinal interest. The research group has gained high credit particularly for the development of Novel Synthetic Methodologies using Benzotriazole methodology, Hypervalent Iodine Reagent, and Ionic liquid in facile synthesis of biologically active molecules etc. Recently, total synthesis of naturally occurring molecules and their derivatives such as imino sugars, amino sugars, Sialic acids, lincomycin analogs, and some simple but biologically important alkaloids were also in the focus. Our ongoing research has been supported for grant-in-aid from funding agency such as DST, New Delhi (2005-2008), CSIR (2008- 2011) and UGC (2009-2012) for that I am really very much thankful.

Teaching Interest: 

His teaching interest covers almost all branch of Organic Chemistry including Organic Synthesis, Reaction Mechanism, Stereochemistry, Symmetry controlled Pericyclic Reactions, Heterocycles, Bio-Organic Chemistry, Medicinal Chemistry, Green Chemistry, Spectroscopy of Organic compounds (NMR, IR etc), and Natural Product Chemistry (Over 8 years teaching experience at UG and PG level).


Problem Set 1 Problem Set 2 Problem Set 3 Problem Set 4
Projects Undertaken as PI: Completed Three Project (DST, CSIR, and UGC)
SN PROJECT TITLE DURATION AGENCY
1 Design and development of Novel antimicrobial agents. 2006- 2009 DST, New Delhi
2 Design and development of Carbohydrate based biodynamic agents. 2008-2011 CSIR, New Delhi
3 Development of novel synthetic methodology using Benzotriazole chemistry and their applications. 2009-2012 UGC, New Delhi


Awards/ Honors/ Recognitions (Selected List):

  • Chemical Research Society of India (CRSI), Young Scientist Award-2012

  • Dr. Ghanashyam Srivastava Memorial Medal-2012, Indian Chemical Society.

  • 1st Dr. H C Srivastava Award-2012, Association of Carbohydrate Chemist & Technologist.

  • 1st Tatva Scientist of the Year Award-2014, International Academy of Physical Sciences.

  • Prof. R C Shah Memorial Lecture Award-2011, Indian Science Congress Association.

  • Dr. Arvind Kumar Memorial Award-2010, Indian Council of Chemist.

  • Young Scientist Award-2010, U.P. Council of Science & Tech., Govt. of U.P.

  • Bibliography included in Marquis Who's Who in world-2011

  • Dr. Sam Hangimbottom Memorial Lecture-2011.

  • NESA GOLD Medal-2010, Jr. Scientist of the Year Award.

  • Most Cited Award Paper-2006, Elsevier Publications for our BMC-2003.

  • DST FAST Track Award for Young Scientist-2005.

  • Dr. D. S. Bhakuni Award-2004, by Indian Chemical Society.

  • �Young Investigator Prize� by ICRABTS-2004, held at Bundelkhand University, Jhansi, 13-15th January 2004 and offered for the post of Lecturer (position availed for 18 month).

  • Numerous invited lectures (over 45) at different institution such as Bhawnagar University, Banaras Hindu University; Bundelkhand University, Jhansi; University of Delhi; Algappa University, Karaikuddi; Indian Institute of Technology, Delhi; Indian Institute of Technology, Chennai; Udai Pratap College, Varanasi; Harish Chandra College, Varanasi; Baldev PG College, Varanasi; Hyderabad University, Hyderabad; Kalyani University; M. S. University, Baroda; IGCAR, Kalpakkam; KIIT University, Bhuwneshwar; CTCRI, Trivendrum; Central Drug Research Institute, Lucknow; Punjab University, Chandigarh; Himachal Pradesh University, Shimla; Indian Institute of Chemical Technology, Hyderabad; Universitat Konstanz, Germany; University of California; SRMS Institute of Science & Tech, Barely, International Conference of Physical Sciences at Bancock (Invited) etc.

  • Editor, Trends Carbohydrate Research; Facilitator, ARKIVOC for special issue to Honor Prof. Richard R Schmidt; Editor, Opportunity, Challenge and scope of Natural Products in Medicinal Chemistry; Editorial Board of Referee, ARKIVOC and Reviewers of several Journals (ACS, RSC, Wiley, Elsevier, Bentham, Springer, Theim, etc.

  • List of Ten Representative Publications:

  • Chemoenzymatic synthesis of GD3 oligosaccharides and other disialyl glycans containing natural and non-natural sialic acids, J. Am. Chem. Soc., 2009, 131, 18467-18477.

  • Synthesis, molecular modeling and antitubercular activities of glycopeptide analogs with both furanose and pyranose ring structures, J. Comb. Chem., 2009, 11, 422-427.

  • Diacetoxyiodobenzene Mediated One-Pot Synthesis of Diverse Carboxamides from Aldehydes, Org. Lett., 2012, 14, 2936-2939.

  • Disaccharide Containing Macrocycles through Click Chemistry and Intramolecular Glycosylation, Eur. J. Org. Chem., 2012, 2945-2956.

  • A Highly Expeditious Synthesis of Bicyclic Iminosugar using Novel key step of [NMM]+ [HSO4]- promoted Conjugate Addition and Mitsunobu Reaction, RSC Adv., 2013, 3, 5794-5797.

  • Structural Basis for Substrate Specificity and Mechanism of N-Acetyl-D-neuraminic Acid Lyase from Pasteurella multocida, Biochemistry, 2013, 52, 8570- 8579.

  • Synthesis of Glycoconjugate Benzothiazoles via cleavage of Benzotriazole Ring, J. Org. Chem., 2013, 78, 899-909.

  • Click Chemistry inspired Synthesis of Porphyrin Glycodendrimers, J. Org. Chem., 2013, 78, 8184-8190.

  • Synthesis of 2-N/S/C-substituted Benzothiazoles via Intramolecular Cyclative Cleavage of Benzotriazole Ring, J. Org. Chem., 2014, 79, 251-265.

  • Click Chemistry Inspired Synthesis of Diverse Morpholine-fused Triazoles, J. Org. Chem., 2014, 79, DOI: DOI:/10.1021/jo500890w. .

  • Editorial and other Assignments:

  • Editorial and other Assignment:

  • Editor, Trends Carbohydrate Research

  • Editor, Int. J. Carbohydrate Chemistry

  • Facilitator, ARKIVOC for special issue to Honor Prof. Richard R Schmidt

  • Editor, Biochemical Compounds

  • Editor, Opportunity, Challenge & scope of Natural Products in Medicinal Chemistry

  • Key note speaker (3); Memorial Lecture (5); and numerous Invited lectures (over 55) in India, USA, Germany, Pakistan and Thialand.

  • Visiting Scientist at Department of Chemistry, Universitat Konstanz, Germany (2009).

  • Visiting Post doc through Prof Chen�s Beckman Investigator Award by UC Davis, USA (2007)

  • Adjunct Post-doc Fellow with Prof. A R Katritzky, Director, University of Florida, USA (2005)

  • Qualified various Exam including NET-CSIR-UGC, SET, CDRI, Research Scholarship, JRF at CDRI (2000) and then CSIR-SRF (2002), GATE-2000 with 95.7 percentile.

  • 2nd University Rank in BHU (MSc: 1996-1998); Rank in RET-BHU (1998); BHU scholarship (Jan 1999 - March 2000); Merit scholarship during high school (1988-1989).

  • Published articles receiving good citation (over 1460 citations with h-index 22).

  • Reviewers of several journals (RSC, Elsevier, ACS, Springer, Bentham, Wiley etc.).

  • Member of several academic societies, Executive member (ACCTI, 2009-2011).

  • Joint Secretary, Association of Carbohydrate Chemist and Technologists, India (2014-2018).

  • Present Research Members:

List of PATENTS/ PUBLICATIONS:

Total number of Publications: 84; Total number of Patents (Indian) filled: 8
Book Chapters: 10; Edited Book: 1.
H-index = 22; Total number of Citations = 1385; Impact factor: over 210.
Major Research Project completed: 3 (CSIR, DST, and UGC).
PhD thesis completed: 6, Ongoing: 4; MS thesis: 10; Conference organized: 2
Invited lectures: Key note speaker (3), Invited Talk (56), Memorial Lectures (5).

List of PATENTS/PUBLICATIONS (Selected List):

1. Inventors: Ramapati Tripathi, Vinod K Tiwari, A K Srivastava, K Arora, S Gupta, K P Murthy, R D Walter: A process for the preparation of novel N1, Nn-diglycosylated diamino alkanes useful in chemotherapy of filarial infections (INF/PAT/05/2001).

2. Inventors: Ramapati Tripathi, Vinod K Tiwari, A K Srivastava, K Arora, S Gupta, KP Murthy, R D Walter: N1, Nn-diglycosylated diamino alkanes useful in chemotherapy of filarial infectious (INF/PAT/06/2001).

3. Inventors: Ramapati Tripathi, Vinod K Tiwari, R C Mishra, R Srivastava, S Sriwastava, V Chaturvedi, K K Srivastava, B S Srivastava: A process for the preparation of novel combinatorial library of N1 - glycosylated and N3 - substituted ureas and thioureas useful as antitubercular agents, (NF/476/01); Patent Appl. No.-0715DEL2004, Filing date: 15.04.2004

4. Inventors: Ramapati Tripathi, Vinod K Tiwari, R C Mishra, R Srivastava, S Sriwastava, V Chaturvedi, K K Srivastava, B S Srivastava: Novel combinatorial library of N1? glycosylated and N3 ?substituted ureas and thioureas useful as antitubercular agents, (NF/474/01); Patent Appl. No.: 0264DEL2002, Filing Date: 20/03/2002, Patent No.: 199556, Grant Date: 06/10/2006

5. Inventors: Ramapati Tripathi, Vinod K Tiwari, N Tewari, R Srivastava, S Srivastava, V Chaturvedi, K K Srivastava, B S Srivastava: Novel N1, Nn-diglycosylated diaminoalcohol useful in the chemotherapy of ubercular infections. (NF/348/02); Patent Appl. No.-0431NF2004/IN, Filing date: 19.11.2004.

6. Inventors: Ramapati Tripathi, Vinod K Tiwari, N Tewari, R Srivastava, S Sinha, V Chaturvedi, K K Srivastava, B S Srivastava: A process for the preparation of diglycosylated diaminoalcohol as antitubercular agents (NF/349/02).

7. Inventors: Ramapati Tripathi, Vinod K Tiwari, D Katiyar, N Tewari, A Gaikwad, S Sinha, V Chaturvedi, A Srivastava, R Srivastava, B S Srivastava: A process for the synthesis of novel glycosylated amino alcohol as anti-tubercular agents (NF/08/03).

8. Inventors: Ramapati Tripathi, Vinod K Tiwari, D Katiyar, N Tewari, A Gaikwad, S Sinha, V Chaturvedi, A Srivastava, R Srivastava, B S Srivastava: Novel glycosylated aminoalcohol useful in the chemotherapy of tuberculosis (NF/09/03); Patent Appl. No.-1217DEL2004, Filing date: 30.06.2004.

Publications (2002):

9. Unexpected Isomerisation of Double bond with DBU: A Convenient Synthesis of Tetrasubstituted a-alkylidene tetrahydrofuranoses, Tiwari V. K. and Tripathi R. P., Ind J Chem, 2002, 41 B, 1681-1685.

10. Synthesis of Glycosylated b-amino acids as new class of antitubercular agents (2002): Tripathi R. P., Tripathi P., Tiwari V. K.; Bala L.; Sinha S.; Srivastava A; Srivastava R; Srivastava B S, Eur. J. Med. Chem., 37, 9, 773-781.

11. Conjugate addition of amines to sugar derived olefinic ester: synthesis of glycosylated amino esters as DNA Topoisomerase?II Inhibitors, Khan A. R.; Tripathi R. P.; Tiwari V. K.; Mishra R. C.; Reddy V. J. M. and Saxena J. K., J. Carbohyd Chem, 2002, 21(6), 587-600.

12. DBU/ TBAB/4A0 catalysed cyclatic amidation reactions: A highly efficient & convenient synthesis of C-Nucleosides, Tewari N.; Mishra R. C.; Tiwari V. K.; Tripathi R. P., Synlett, 2002, 11, 1779-1782.

13. Tiwari V. K.; Tripathi R. P.; Tripathi R.; Bala L.; Sinha S.; Srivastava R.; Srivastava B.S. Search of new drugs for tuberculosis: Glycosylated b-amino acids as new class of antitubercular agents, Trends in Carbohydrate Chem., 2002, 8, 67-76.

Publications (2003):

14. Amberlite IR -120 Catalysed Efficient Synthesis of Glycosyl Enaminones and their Application, Tewari N.; Katiyar D.; Tiwari V. K., Tripathi R. P., Tetrahedron Lett., 2003, 44, 6639- 6642.

15. Synthesis and Antifilarial Evaluation of N1, Nn- Diglycosylated Diaminoalkanes, Tiwari V. K.; Tewari N.; Tripathi R. P.; Arora K.; Gupta S.; Srivastava A. K.; Khan M. A., Murthy P. K.; Walter R D. Bio-Organic & Medicinal Chemistry, 2003, 11, 1789-1800.

16. Synthesis and bioevaluation of glycosyl ureas as a-glucosidase inhibitors and their effect on Mycobacterium, Tewari N.; Tiwari V. K.; Mishra R. C.; Tripathi R. P.; Srivastava A. K.; Ahmad R.; Srivastava R. and Srivastava B. S. Bio-Organic & Medicinal Chemistry, 2003, 11, 2911-2922 (Received most cited paper award in ACS meeting at Sanfransisco, CA, USA).

17. Synthesis and Antimycobacterial Activity of 3,5-Disubstituted Thiadiazine thiones, Katiyar D.; Tiwari V. K.; Tripathi R. P.; Srivastava A. K.; Chaturvedi V.; Srivastava R. and Srivastava B. S. Bio-Organic & Medicinal Chemistry, 2003, 11, 4369-4375.

18. Combinatorial and conventional synthesis of glycohybrid molecules as new class of anti tubercular agents, Tiwari V K; Tripathi R P; Chaturvedi V; Srivastava A; Sinha S; Srivastava, R.; Srivastava B. S., Med Chem Res, 2003, 12, 394.

19. Combinatorial synthesis of glycohybrid molecules as potential chemotherapeutic agents, Mishra R. C.; Tiwari V. K.; Tripathi R. P., Med Chem Res, 2003, 12, 336.

20. DBU Assisted Cyclorelease Elimination: Combinatorial Synthesis and g-glutamyl cystein synthetase & glutathione-S-transeferase Modulatory Activity of C- nucleoside analogs, Mishra R. C.; Tewari N.; Arora K.; Ahmad R.; Tripathi R. P.; Tiwari V. K.; Walter R. D. and Srivatava A. K., Combi Chem & Highthroughtput Screening, 2003, 6, 36-51.

21. 7-O-(4-methyl piperazin-acetyl)-4-methyl-2H-1-benzopyran-2-ones: A novel lead compound for antifilarial activity, Tripathi R. P.; Tiwari V. K.; Bhattacharya S.; Srivastava K.; Srivastava V. M. L., Murty P. K., Acta Tropica, 2003, 87, 215-224.

22. Synthesis and antifilarial evaluation of 7-O-acetamidyl-4-alkyl-2H-1-benzopyran-2-ones, Katiyar D.; Tiwari V. K.; Tripathi R. P.; Reddy V. J. M.; Bhattacharya S.; Saxena J. K., Arzneimittel Forschung Drug Res., 2003, 53, 12, 857-863.

Publications (2004):

23. Synthesis of Galactopyranosyl Amino Alcohols as a new class of Antitubercular and antifungal agents, Tewari N.; Tiwari V. K.; Tripathi R. P.; Gaikwad A.; Sinha S.; Chaturvedi A. K.; Shukla P. K.; Srivastava R, Srivastava B. S., Bio-Organic & Medicinal Chemistry Letters, 2004, 14, 329-332.

24. An efficient syntheses of a-mannosylated phenolics as a-glycosidase inhibitors, Khan A. R., Tiwari V. K.; Srivastava A. K.; Ahmad R.; Tripathi R. P., J. Enzyme Inhibition and Med. Chem., 2004,19, 107-112.

25. Inhibitors of filarial g-glutamyl cycle enzymes as possible macrofilaricidal agents, Gupta S.; Arora K.; Tiwari V. K.; Tripathi R. P.; Srivastava A. K.; Walter R. D., Med. Chem. Res., 2004, 13, 707-723.

Publications (2005):

26. Synthesis and antimycobacterial activity of glycosylated b-amino alcohols and amines, Katiyar D; Tiwari V K; Tiwari N; Verma S S; Sinha S; Giakwad A; Srivastava A; Chaturvedi V; Srivastava R; Srivastava B S, Tripathi R P, Eur. J. Med. Chem., 2005, 40, 351-360.

27. Fighting Tuberculosis: An old disease with new challenges, Tripathi R P; Tewari N; Dwivedi N, Tiwari V K, Med. Res. Rev., 2005, 25, 93-131.

28. Synthesis of N1, Nn-diglycosylated b-diamino alcohols as new class of antitubercular agents, Tripathi R P; Tiwari V K; Tiwari N; Giakwad A; Sinha S; Srivastava S; Chaturvedi V; Srivastava B. S., Bio-Org. Med. Chem., 2005, 13, 5668-5679.

29. An efficient synthesis of aryloxyphenyl cyclopropyl methanones: A new class of anti-mycobacterial agents (2005): Tewari N; Dwivedi N; Tiwari, V K; Chaturvedi V; Manju Y K; Srivastava A; Giakwad A; Sinha S; Tripathi R. P., Bio-Org. Med. Chem. Lett., 2005, 15, 4526-4530.

Publications (2006):

30. Synthesis and antitubercular activities of substituted benzyl- and heteroaryl amines, N Saxena, SS Verma, V K Tiwari, V Chaturvedi, YK Manju, AK Srivastva, A Gaikwad, S Sinha, RP Tripathi, Bio-Org & Med. Chem., 2006, 14, 8186-8196.

31. 7-isovarleryloxy-8-methoxygirinimbine: A new carbazole alkaloid from Murraya koenigii, B B Mishra, V K Tiwari, D D Singh, Archana Singh, V J Tripathi, Med. Chem. Res., 2006, 15, 119-120.

32. Benzotriazole mediated one pot convenient synthesis of Thioquinazolinones as potential Antifungal agents, V K Tiwari,* H A Hussain, B B Mishra, D D Singh, V J Tripathi, Med. Chem. Res., 2006, 15, 325-327.

Publications (2007):

33. Synthesis and Antitubercular Activities of S-Glycosyl Mercaptans, Tiwari V K; Singh B K; Chaturvedi V; Manju Y K; Srivatava A K; Sinha S; Gaikwad A, Tripathi R P, Organic Chem: An Ind J, 2007, 3(2), 84-96 (Invited paper).

34. Sustained release bi-layered tablets of domperidone maleate using hydrophilic matrix system, Pandey H; Tiwari V K; Prajapati S K, Ind. Drug, 2007, 44, 261-263.

35. One-pot convenient and high yielding synthesis of dithiocarbamates, V K Tiwari,* A Singh, H A Hussain, B B Mishra, V J Tripathi Monatsh Chemie, 2007, 138: 534- 538.

36. One pot amberlite IR-120 catalyzed synthesis of glycosyl pyridinone, Tiwari V K Tewari N, D Katiyar, Tripathi R P, Monatsh Chemie, 2007, 138: 1297-1302.

Publications (2008):

37. One-pot, simple new, and convenient synthesis of 2-Thioxo-2,3-dihydroquinazolin-4(1H)-ones, V K Tiwari,* D D Singh, H A Hussain, B B Mishra, A Singh, Monatsh Chemie, 2008, 139: 43-48.

38. Recent developments in Catalytic Reductive Amination and Applications, RP Tripathi, SS Verma, J Pandey, V K Tiwari, Current Organic Chemistry, 2008, 12, 1093-1115 [Recognized as most downloaded article].

39. Microwave-assisted one-pot, facile synthesis of 2-Thioxo-2,3-dihydroquinazolin-4(1H)-ones, V K Tiwari,* RR Kale, BB Mishra, A Singh ARKIVOC, 2008, XIV, 26- 35.

40. Pasteurella multocida sialic acid aldolase: a promising biocatalyst (2008): Y Li, H Yu, H Cao, K Lau, S Muthana, V K Tiwari, B. Son, Xi Chen, Applied Microbiology Biotechnology, 2008, 79, 963-970.

41. Multifunctionality of Campylobacter jejuni sialyltransferase CstII: Characterization of GD3/GT3 oligosaccharide synthase, GD3 oligosaccharide sialidase and trans-sialidase activities, J Cheng, H Yu, K Lau, S Huang, HA Chokhawala, Y Li, V K Tiwari, Xi Chen,* GLYCOBIOLOGY, 2008, 18, 686-697.

Publications (2009):

42. Fighting against Leishmaniasis: Search for true anti-leishmanial Alkaloids (2009): B B Mishra, V K Tiwari, V Tripathi, R K Singh, , Mini-Rev. Med. Chem., 2009, 9, 107-123.

43. Synthesis and antitubercular screening of imidazole based molecules, J. Pandey, V K Tiwari, S. S. Verma, R. P. Tripathi, S. Sinha, Eur. J. Med. Chem., 2009, 44, 3350- 3355.

44. Synthesis, molecular modeling and antitubercular activities of glycopeptide analogs with both furanose and pyranose ring structures, J Pandey, A Sharma, V K Tiwari, D Dube, R Ramachandran, V Chaturvedi, S Sinha, N N Mishra, P K Shulka, R P Tripathi, J. Comb. Chem., 2009, 11, 422-427.

45. Alkaloids to combat leishmaniasis, BB Mishra, R K Singh, R R Kale, V K Tiwari*, Fitoterapia, 2009, 80, 81-90 [Most downloaded paper, Science Direct TOP25 Hottest Articles].

46. Alkaloids as potential Anti-tubercular agents, N Kishore, BB Mishra, V Tripathi, V K Tiwari*, Fitoterapia, 2009, 80, 149-163 [Most downloaded paper, Science Direct TOP25 Hottest Articles, most cited article].

47. Benzotriazole mediated one-pot facile synthesis of N/S/N,S-glycosyl dithiocarbamates, A Singh, R R Kale, V. K. Tiwari,* Trends Carbohydrate Chemistry, 2009, 1(1), 80- 85 ][Invited article].

48. Hypervalent Iodine Reagents in Carbohydrate Modifications, V Prasad, R R Kale, BB Mishra, VK Tiwari,* Trends Carbohydrate Research, 2009, 1(4), 43-49.

49. Chemoenzymatic synthesis of GD3 oligosaccharides and other disialyl glycans containing natural and non-natural sialic acids, H Yu, J Cheng, L Ding, Z Khedri, Y Chen, K Lau, V K Tiwari, Xi Chen, J. Am. Chem. Soc., 2009, 131, 18467-18477.

Publications (2010):

50. A novel antifungal anthraquinone from seeds of Aegle marmelos Correa (Rutaceae), N Kishore, BB Mishra, VK Tiwari, V Tripathi, Fitoterapia, 2010, 81, 104-107.

51. Antifungal constituents isolated from the seads of Aegle marmrlos, B B Mishra, D D Singh, N Kishore, V K Tiwari, V Tripathi, PHYTOCHEMISTRY, 2010, 71, 230- 234.

52. Difuranonaphthoquinones from Plumbago zeylanica roots, N Kishore, B B Mishra, V K Tiwari, V Tripathi, Phytochemistry Letters, 2010, 3, 62-65.

53. Bis(benzotriazol-1-yl)methanethione: Non-toxic versatile thiophosgene equivalent, A Singh, R R Kale, B B Mishra, V Tripathi, V K Tiwari*, J. Scientific Res., 2010, 50, 118- 130 [Bis (benzotriazol-1-yl)methanethione, Spotlight by A Singh, SYNLETT, 2010, 13, 2045-2046.

54. Antifungal constituents isolated from seeds of Aegle Marmelos Corr (Family-Rutaceae), B B Mishra, N Kishore, V K Tiwari, D D Singh, V Tripathi, Med. Chem. Res., 2010, 19, S60-61.

55. Benzotriazole mediated facile synthesis of Carbohydrate based potential chemotherapeutic agents, R R Kale, Archana Singh, V Prasad, V Tripathi, V K Tiwari, Med. Chem. Res., 2010, 19, 107 [IF = 1.058].

56. Facile synthesis of novel carboxamide both with furanose and pyranose sugar (2010): R R Kale, V Prasad, V K Tiwari,* Lett. Org. Chem., 2010, 7, 136-143.

57. Carbohydrate Chemistry and Room Temperature Ionic Liquids: Recent developments, Opportunity and Challenges (2010): V Prasad, R R Kale, V Kumar, V K Tiwari*, Current Organic Synthesis, 2010, 7, 506-531.

58. Recent development on benzotriazole mediated heterocyclization to construct pharmacologically active heterocyclic skeleton (2010): RR Kale, V Prasad, P P Mohapatra, V. K. Tiwari*, Monashefte Chemie, 2010, 141, 1159-1182.

59. A Novel Naphthoquinone from Plumbago zeylanica Roots (2010): N Kishore, B B Mishra, V K Tiwari, V Tripathi, Chemistry Natural Compounds, 2010, 46 (4), 517-519 [highlighted in Khimiya Prirodnykh Soedinenii, 2010, 4, 439?440].

60. Facile route for N1-aryl benzotriazoles from diazoamino arynes via CuI-mediated intramolecular N-arylation, R R Kale, H A Hussain, V Prasad, V K Tiwari*, Tetrahedron Letters, 2010, 51, 5740-5743.

Publications (2011):

61. Facile route for novel quinazolinone-fused azauracils through cyclodesulfurization of thioquinazolinones, R R Kale, V Prasad, V K Tiwari,* SYNLETT, 2011, 2, 195-198.

62. Naturally Occurring Bioactive C-Glycosides, N Kishore, B B Mishra, V Tripathi, V K Tiwari, Trends Carbohydrate Chem, 2011, 3(1), 1-12.

63. Chemoenzymatic synthesis of C8-modified sialic acids and related alpha 2?3- and alpha 2?6-linked sialosides, H Yu, H Cao, V K Tiwari, Y Li, Xi Chen, Bio-Org Med. Chem. Lett., 2011, 21, 5037-5040.

64. Targeting Leishmania Species: Nanotechnological Prospects, R. K. Singh, A. Srivastava, J. K. Gour, V. K. Tiwari, Adv. Science Lett., 2012, 5, 1?10.

65. A sialylated glycan microarray reveals novel interactions of modified sialic acids with proteins and viruses, R D Cummings, J H Molinaro, X Song, H Yu, X Chen, Y Lasanajak, M M Tappert, G M Air, V K Tiwari, H Cao, H A Chokhawala, H Zheng, D F Smith, J. Biol. Chem., 2011, 286, 31610-31622.

66. Substrate Promiscuity of N-Acetylhexosamine 1-Kinases (2011): Y Li, H Yu, Y Chen, Kam Lau, Li Cai, H Cao, V. K. Tiwari, J Qu, V Thon, P G Wang, Xi Chen, Molecules, 2011, 16(8), 6396-6407.

67. Nature?s Pharmacophoric Libraries: An evolving role in future drug discovery (2011): B B Mishra, V K Tiwari*, Eur. J. Med. Chem., 2011, 46, 4769-4807 [recognized as the most read article].

Publications (2012):

68. Facile synthesis of Novel Glycosyl Azetidine under mild reaction condition, A Singh, BB Mishra, RR Kale, V K Tiwari,* Synthetic Commun, 2012, 42, 3598-3613.

69. Facile synthesis of Glycosyl Tetrazole using Benzotriazole Methodology, R R Kale, V Prasad, D Kushwaha, V K Tiwari,* J. Carbohydrate Chem., 2012, 31, 130-142.

70. Targeting Leishmania Species: Nanotechnological Prospects, R. K. Singh, A. Srivastava, J. K. Gour, V. K. Tiwari, Adv. Science Lett., 2012, 5, 1-10.

71. Cyclorelease strategy in Solid-Phase Combinatorial synthesis of heterocyclic skeletons, B B Mishra, D Kumar, A Mishra, P P Mohapatra, V K Tiwari*, Adv. Heterocyclic Chem., 2012, 107, 41-99 (Invited article).

72. An account of phytochemials from Plumbago zeylanica (Family-Plumbaginaceae): A natural gift to human being, N Kishore, BB Mishra, V K Tiwari, V Tripathi, Chronical Young Sc., 2012, 3, 178-198 [Invited article

73. Cu(acac)2 mediated Azide-Alkyne Cycloaddition for an easy access of Regioselective Triazolyl Glycoconjugates, D Kushwaaha, P Pandey, R R Kale, V K Tiwari,* Trends Carbohydrate Res., 2012, 4(3), 45-53.

74. Solid-Phase Combinatorial Synthesis of Carbohydrate-containing Ureas with Four point Diversity, R P Tripathi, R C Mishra, V K Tiwari, Trends Carbohydrate Res., 2012, 4(3), 28- 44.

75. Disaccharide Containing Macrocycles through Click Chemistry and Intramolecular Glycosylation, V. K. Tiwari, A Kumar, R R Schmidt,* Eur. J. Org. Chem., 2012, 2945-2956.

76. Carbohydrate-based Potential Chemotherapeutic Agents: Recent Developments and their Scope in Future Drug Discovery, V K Tiwari, R C Mishra, A Sharma, R P Tripathi,* Mini- Rev. Med. Chem., 2012, 12, 1497-1519 (Invited article).

77. Diacetoxyiodobenzene Mediated One-Pot Synthesis of Diverse Carboxamides from Aldehydes, V Prasad, R R Kale, B B Mishra, D Kumar, V K Tiwari,* Org. Lett., 2012, 14, 2936-2939

Publications (2013):

78. Synthesis of Glycoconjugate Benzothiazoles via cleavage of Benzotriazole Ring, D Kumar, A Mishra, B B Mishra, S Bhattacharya, V K Tiwari,* J. Org. Chem., 2013, 78, 899-909.

79. Click reaction in Carbohydrate Chemistry: Recent development and future perspective, D Kushwaha, P Dwivedu, S K Kuawar, V K Tiwari*, Curr. Org. Syn., 2013, 9(2), 89-135.

80. A tribute to Prof. Richard Schmidt (RS-1462IT), Vinod Tiwari (Facilitator), ARKIVOC, 2013, ii, 1-5.

81. A Highly Expeditious Synthesis of Bicyclic Iminosugar using Novel key step of [NMM]+[HSO4]- promoted Conjugate Addition and Mitsunobu Reaction, V Prasad, D Kumar, V K Tiwari*, RSC Adv., 2013, 3, 5794-5797.

82. An Anti-Leishmanial Naphthoquinone from Roots of Plumbago zeylanica (Family-Plumbaginaceae), BB Mishra, J K Gaur, N Kishore, V Tripathi, R K Singh, V K Tiwari,* Nat. Prod. Res., 2013, 27, 480-485.

83. Synthesis of fluorescent meso-glycosyl dipyrromethanes as probes for Cu2+/Cd2+ Ions, A Biswas, R Pandey, D Kushwaha, M Shahid, VK Tiwari, A Mishra, DS Pandey, Tetrahedron Lett., 2013, 54, 4193-4197.

84.Synthesis of 2?-N-benzotriazole-2,3:5,6-di-O-isopropylidene-?-D-mannofuranoside using benzotriazole methodology, D Kumar, V. K. Tiwari*, Trends Carbohyd. Res., 2013, 5(3), 44-48.

85. Recent Development on Heterocyclic synthesis through the cleavage of benzotriazole ring, D Kumar, B B Mishra, R R Kale, K B Mishra, V K Tiwari*, Signpost Open Access J. Org. Biomol. Chem., 2013, 1, 169-186 [invited article].

86. Natural Products as Leads to Potential Mosquitocides, N Kishore, B B Mishra, V K Tiwari, V Tripathi, N Lall, Phytochem. Rev., 2013, DOI: 1007/s11101-013-9316-2.

87. Structural basis for substrate specificity and mechanism of N-acetyl-D-neuraminic acid lyase from Pasteurella multocida, N Huynh, A Aye, Y Li, H Yu, H Cao, V K Tiwari, D-W Shin, Xi Chen, A J Fisher, Biochemistry, 2013, 52, 8570�8579.

88. Click Chemistry inspired Synthesis of Porphyrin Glycodendrimers, D Kushwaha and V K Tiwari*, J. Org. Chem., 2013, 78, 8184-8190.

Publications (2014):

89. Highly facile Synthesis of diverse N-, C- and S-substituted Benzothiazoles, D Kumar, B B Mishra, V K Tiwari,* J. Org. Chem., 2013, 79, 251-265.

90. Click chemistry inspired Facile Synthesis of triazolyl ethisterone glycoconjugates, D Kumar, K B Mishra, S Mondal, B B Mishra, V K Tiwari*, Steroids, 2014, 80, 71-79.

91. Cu-Catalyzed Click Reaction in Carbohydrate Chemistry, B B Mishra, D Kushwaha, Xi Chen, V K Tiwari, Chem. Rev., 2013 (proposal accepted on 17/7/2013, Ref. Tiwari cr- 2013-003038).

92. Natural Products as leads to Fight against Leishmaniasis, N Singh, M R Gedda, B B Mishra, R. K. Singh, V. K. Tiwari,* Bio-Org. Med. Chem., 2013, 22, 18-45 [recognized as the most read article].

93. Carbohydrate based Fluorescent sensor for the selective determination of Cu2+, D Kushwaha, R Singh, V K Tiwari,* Tetrahedron Lett., 2014 (under revision)

94. Click Chemistry Inspired Synthesis of Diverse Morpholine-fused Triazoles, K B Mishra and V K Tiwari,* J. Org. Chem., 2014, 79, DOI:/10.1021/jo500890w.

95. An unexpected PTSA catalyzed 1,3-migration of thiocarbonyl: Selective formation of more stable five membered 1,3-dioxolane-2-thione ring and Optimization Study, D Kumar, A S Singh, V K Tiwari*, Trends Carbohydrate Res., 2014, accepted for publication.

96. Regioselective Synthesis of Novel Isoxazole-linked Glycoconjugates, A Mishra, B B Mishra, Eur. J. Org. Chem., 2014 (submitted ejoc.201402590).

97. Highly facile Synthesis of Glycosyl-?-Azidoester and its Application towards Development of Glycosyl Triazoles, 2014 (submitted).

98. Facile Synthesis of Steroidal triazolyl glycoconjugate, K B Mishra, B B Mishra and V K Tiwari*, Carbohydrate Res., 2014 (Submitted).

99. Click Chemistry inspired synthesis and anti-leishmanial activity of Flavone triazolyl glycoconjugates, P Dwivedi, K B Mishra, B B Mishra, R K Singh, V K Tiwari*, ACS Combi. Sc., 2014 (submitted).

100. Synthesis, structure and catalytic activities of new Cu(I) thiocarboxylate complexes, D Joshi, K B Mishra, V K Tiwari, S Bhattacharya, 2014 (to be submitted).

101. Deoxygenation of benzylic alcohols using benzotriazole methodology: Bis(benzotriazole) methanethione as an imperative synthetic auxiliary, D Kumar and V K Tiwari,* 2014 (submitted).

Chapter in Book:

102. Search of new drugs for tuberculosis: Glycosylated b-amino acids as new class of antitubercular agents, Tiwari V. K.; Tripathi R. P.; Tripathi R.; Bala L.; Sinha S.; Srivastava R.; Srivastava B.S., Trends Carbohydrate Chem., 2002, 8, 67-76.

103. Natural Products in Drug Discovery: Clinical Evaluations and Investigations, B. B. Mishra, V. K. Tiwari, Book-Review on �Opportunity, Challenge and Scope of Natural products in Medicinal Chemistry-ISBN: 978-81-308-0448-4, 2011, pp 1-62, ed. V. K. Tiwari, Co-Ed BB Mishra.

104. Scope of Natural Products in Fighting against Leishmaniasis, B. B. Mishra, R. R. Kale, V Prasad, V. K. Tiwari, R. K. Singh, Book on �Opportunity, Challenge and Scope of Natural products in Medicinal Chemistry�, 2011, pp 121-154, Ed. V K Tiwari, Co-Ed BB Mishra.

105. Review on Natural Products with Mosquitosidal Potentials, N. Kishore, B. B. Mishra, V. K. Tiwari, V. Tripathi, Book on �Opportunity, Challenge and Scope of Natural products in Medicinal Chemistry�, 2011, 335-366, Ed. V K Tiwari, Co-Ed BB Mishra.

106. Phytochemical Profile of Aegle marmelos (family-Rutaceae), B B Mishra, N Kishore, V K Tiwari, V Tripathi, Book (ed. V. K. Gupta) on Medicinal Plants: Phytochemistry, Pharmacology and Therapeutics, 2012, p 121-154 (Invited article).

107. Impact of Solid-supported Cyclization-Elimination Strategies towards the Natural Product Inspired Molecules in Drug Research, D Kumar, D Kushwaha, B B Mishra, V K Tiwari*, in Bioactive Natural Products, 2012, p 9-30; ed. G Brahmachari, CRC Press, Taylor & Francis Group, USA (Invited article).

108. Scope of Alkaloids in Antileishmanial Drug Discovery and Development, B B Mishra, N Kishore, R K Singh, V K Tiwari,* in Handbook of Natural Products, Springer Publication, 2013, pp 1263-1299 (eds. K G Ramawat, J-M Merillon, Invited article).

109. Emerging role of Room Temperature Ionic Liquids in Carbohydrate Modification, V Prasad, D Kushwaha, K Mishra, L Mishra, V K Tiwari*, Adv. Org. Syn., 2013, 4, 345-408 (ed. Atta-ur-Rahman, Invited article).

110. Triazolyl Glycoconjugates in Medicinal Chemistry, Tripathi, R. P., Dwivedi, P., Sharma, A., Kushwaha, D. and Tiwari, V. K., 2013, pp. 293-323, in Click Chemistry in Glycoscience: New Developments and Strategies (eds Z. J. Witczak and R. Bielski), John Wiley & Sons, Inc., Hoboken, NJ, USA. doi: 10.1002/9781118526996.ch12 (Invited article)

111. Five and six-membered heterocyclic synthesis using Ionic Liquids, in Green Synthetic Approaches for Biologically Relevant Heterocycles, B B Mishra, D Kumar, R P Tripathi, V K Tiwari* (2013), Elsevier Publication, Ed. G Brahmachari (Invited article).

Edited Book: Opportunity, Challenge and Scope of Natural products in Medicinal Chemistry-ISBN: 978-81-308-0448-4?, Editor: V K Tiwari & B B Mishra (2011). http://www.trnres.com/ebookcontents.php?id=95