Dr. Kiran Singh |
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Associate Professor
Ph.D (BHU)
Contact Information:
Tel.+91-542-6702489;, +91-78809345459(mobile) Fax +91-542-6702499
Email Id:[email protected] ; [email protected] |
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Academic Qualifications: | |
S. No. | Degree | Institution | Year |
1. | B.Sc. | U.P College,Varanasi | 1998 |
2. | M.Sc. | Pondicherry Central University | 2000 |
3. | Ph.D | Banaras Hindu University | 2006 | |
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Area of specialization: |
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(Major Scientific fields of interest)
- Molecular Human Reproductive Genetics
- Clinical cytogenetics
- Genetic of Gynaecological malignancies
Current research focus
- Reproductive dysfunction is a diverse, multifactorial group of disorders affecting the potential to procreate. It can affect either of the sexes with similar outcome, infertility. At least 20% of these cases are idiopathic. There is a strong reason to suspect that genetic predisposition may play an important role in these cases. My focus of research is on understanding the molecular/genetic contribution to infertility in both sexes, early pregnancy loss and polycystic ovarian syndrome. Using cytogenetic and molecular approaches, I propose to unravel the relative contribution of genetic risk factors and their modulation by environment in causing infertility. Genomic and proteomic approaches are being applied to get a wholesome picture of the reproductive failure in both sexes. Identification of effective molecular biomarkers for diagnosis/prognosis which may assist in developing better management strategies.
Future vision:
- Identification of potential genetic biomarkers for reproductive disorders and translational approach to for therapy and management.
Awards:
- Senior Research Fellowship (graduate study), Council of Scientific and Industrial Research (CSIR), Govt. of India (2004 �present)
- Junior Research Fellowship (graduate study), University Grants Commission (UGC), Govt. of India (2001- 2004).
- Merit fellowship (Masters study), Department of biotechnology, Govt. of India (1998)
- Merit certificate, in QUEST-93 (A Science competition) organized by Student Welfare Society (Regd.), Uttar Pradesh (1994).
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Current Research Projects: |
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S. No. | Name of the Project | Duration | Source of Funding | Amount of Funding (Rs) |
1. | Novel Biomarkers of sperm quality assessment and aberrant epigenetic modifications in male infertility (P.I) | 2018- 2021 | ICMR, New Delhi | 49.9 lacs |
2. | Myeloid Derived suppressor cells in maternal fetal tolerance: A potential therapeutic target in early miscarriage patients | 2016-2019 | DBT, New Delhi | 80.50 lacs |
3. | Genetic Awareness, Diagnostic and Counseling Programme on Maternal and Neonatal Health (PI) | 2016- 2019 | DBT, New Delhi | 59.79 Lacs |
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10 major publications:
- 1. Singh V, Jaiswal D, Singh K, Trivedi S, Agrawal NK,Gupta G, Rajender S, Singh K (2019) Azoospermic infertility is associated with altered expression of DNA repair
genes. DNA Repair 75/39-47
- 2. Sujit KM, Sarkar S, Singh V, Pandey R, Agrawal NK, Trivedi S, Singh K, Gupta G, Rajender S (2018) Genome-wide differential methylation analyses identifies methylation signatures of male infertility. Human Reproduction. 2018 Oct 25.doi.org/10.1093/humrep/dey319
- 3. Budhwar S, Verma P, Verma R, R Sangeeta, Singh K (2018) The Yin and Yang of Myeloid Derived Suppressor Cells. Frontiers in Immunology.doi: 10.3389/fimmu.2018.02776 (In press)
- 4. Kumar V, Soni UK, Maurya VK, Singh K, Jha RK (2017) Integrin beta8 (ITGB8) activatesVAV-RAC1 signaling via FAK in the acquisition of endometrial epithelial cell receptivity for blastocyst implantation, Scientific Report, 7 (1885),
DOI:10.1038/s41598-017-01764-7
- 5. Bansal SK, Jaiswal D, Gupta N, Singh K, Dada R, Sankhwar S, Singh R. (2016) Gr/gr deletions on Y-chromosome correlate with male infertility: an original study, meta-analyses, and trial sequential analyses. Scientific Reports,doi:10.1038/srep19798.
- 6. Sujit KM, Sarkar S, Singh V, Pandey R, Agrawal NK, Trivedi S, Singh K, Gupta G, Rajender S (2018) Genome-wide differential methylation analyses identifies methylation signatures of male infertility. Human Reproduction. 2018 Oct 25.doi.org/10.1093/humrep/dey319
- 7. Jaiswal D, Trivedi S, Agrawal NK and Singh K. (2015) Dysregulation of apoptotic pathway candidate genes and proteins in infertile azoospermia patients. Fertility and Sterility, 104 (3), 736-743. e6doi.org/10.1016/j.fertnstert.2015.05.029
- 8. Nair RR, Khanna A, Singh K. (2015) Reduced myeloid-derived suppressor cells in the blood and endometrium is associated with early miscarriage. American Journal of Reproductive Immunology, 73(6):479-86.doi.org/10.1111/aji.12351
- 9. Nair RR, Khanna A, Singh R, Singh K. (2013) Association of Maternal and Fetal MTHFR A1298C polymorphism with the risk of pregnancy loss - A Study on an Indian Population and a Meta-Analysis. Fertility and Sterlity. 99 (5): 1311-1318.e4. DOI: 10.1016/j.fertnstert.2012.12.027
- 10. Singh K, Jaiswal D. One-carbon metabolism, spermatogenesis, and male infertility. Reproductive Sciences. 2013 Jun;20(6):622-30. doi: 10.1177/1933719112459232.
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A. Full List of publications:
- 72. Singh V, Jaiswal D, Singh K, Trivedi S, Agrawal NK,Gupta G,Rajender S,Singh K (2019) Azoospermic infertility is associated with altered expression of DNA repair genes. DNA Repair 75/39-47
- 71. Singh V ,Mohanty SK,Verma P,Chakraborty A,Trivedi S,Rajender S,Singh K (2019) XRCC1 deficiency correlates with increased DNA damage and male infertility. Mutat Res Gen Tox En 839/1-8
- 70. Verma, P., Verma, R., Nair, R.R., Budhwar, S., Khanna, A., Agrawal, N.R., Sinha, R., Birendra, R., Rajender, S. and Singh, K (2018) Altered crosstalk of estradiol and progesterone with Myeloid derived suppressor cells and Th1/Th2 cytokines in early miscarriage is associated with early breakdown of maternal-fetal tolerance. American Journal of Reproductive Immunology.doi: 10.1111/aji.13081
- 69. Budhwar S, Verma P, Verma R, R Sangeeta, Singh K (2018) The Yin and Yang of Myeloid Derived Suppressor Cells. Frontiers in Immunology.doi: 10.3389/fimmu.2018.02776 (In press)
- 68. Mishra P, Negi MP, Srivastava M, Singh K, Rajender S. Decline in seminal quality in Indian men over the last 37 years. Reproductive Biology and Endocrinology. 2018 Dec;16(1):103.doi.org/10.1186/s12958-018-0425-z
- 67. Sujit KM, Sarkar S, Singh V, Pandey R, Agrawal NK, Trivedi S, Singh K, Gupta G, Rajender S (2018) Genome-wide differential methylation analyses identifies methylation signatures of male infertility. Human Reproduction. 2018 Oct 25.doi.org/10.1093/humrep/dey319
- 66. Singh V, Bansal SK, Sudhakar DV, Chakraborty A, Trivedi S, Gupta G, Thangaraj K, Rajender S, Singh K. (2018) SNPs in ERCC1, ERCC2, and XRCC1 genes of the DNA repair pathway and risk of male infertility in the Asian populations: association study, meta-analysis, and trial sequential analysis. Journal of Assisted Reproduction and Genetics. 2018:1-2.doi.org/10.1007/s10815-018-1339-6
- 65. Verma R, Verma P, Budhwar S, Singh K. (2018) S100 proteins: An emerging cynosure in pregnancy and adverse reproductive outcome. Indian Journal of Medical Research (Accepted).
- 64. Verma P, Nair RR, Singh S, Rajender S, Khanna A, Jha RK, Singh K. (2018) High Level of APOA1 in Blood and Maternal Fetal Interface Is Associated With Early Miscarriage. Reproductive Sciences. 2018 Jan 1:1933719118783266.doi.org/10.1177/1933719118783266
- 63. Verma P, Nair RR, Budhwar S, Singh V, Bala R, Khanna A, Agarwal NR, Rai P, Rajender S, Singh K (2018). Interleukin-17 gene polymorphisms and the risk of early miscarriage: A case-control study and meta-analysis. Meta Gene. 2018 Jun 19.doi.org/10.1016/j.mgene.2018.06.012
- 62. Singh, K., Goyal, P., Singh, M., Deshmukh, S., Upadhyay,D., Kant, S., Agrawal, N.K., Gupta, S.K. &Singh, K., Association of Functional SNP-1562C > T in MMP9 Promoter with Proliferative Diabetic Retinopathy in north Indian type 2 Diabetes Mellitus patients, Journal of Diabetes and Its Complications (2017), doi:10.1016/j.jdiacomp.2017.08.010
- 61. Kumar V, Soni UK, Maurya VK, Singh K, Jha RK (2017) Integrin beta8 (ITGB8) activatesVAV-RAC1 signaling via FAK in the acquisition of endometrial epithelial cell receptivity for blastocyst implantation, Scientific Report, 7 (1885), DOI:10.1038/s41598-017-01764-7
- 60. Budhwar S, Singh V, Verma P, Singh K (2017) Fertilization failure and gamete health: Is there a link?, Frontiers In Bioscience, 9, 395-419.
- 59. Sinha P, Singh K, Sachan M (2017) Heterogeneous pattern of DNA methylation in developmentally important genes correlates with its chromatin conformation, BMC Molecular Biology, 18 (1), doi 10.1186/s12867-016-0078-4.
- 58. Singh, K., Agrawal, N. K., Gupta, S. K., Mohan, G., Chaturvedi, S., & Singh, K. (2016). Increased expression of endosomal members of toll-like receptor family abrogates wound healing in patients with type 2 diabetes mellitus. International wound journal, 13(5), 927-935.doi.org/10.1111/iwj.12411
- 57. Kaur M, Singh A, Singh K, Gupta S, Sachan M (2016)Development of a multiplex MethyLight assay for the detection of DAPK1 and SOX1 methylation in epithelial ovarian cancer in a north Indian population, Genes Genetics System, 91, 175-181.doi.org/10.1266/ggs.15-00051
- 56. Nair RR, Verma P, Singh K (2016) Immune-endocrine crosstalk during pregnancy, General of Comparative Endocrinology. doi: 10.1016.
- 55. Bansal SK, Jaiswal D, Gupta N, Singh K, Dada R, Sankhwar S, Singh R. (2016) Gr/gr deletions on Y-chromosome correlate with male infertility: an original study, meta-analyses, and trial sequential analyses. Scientific Reports, doi:10.1038/srep19798.
- 54. Carlus SJ, Sarkar S, Bansal SK, Singh V, Singh K, Jha RK, Sadasivam N, Sadasivam SR, Gireesha PS, Thangaraj K, Rajender S (2016) Is MTHFR 677 C>T Polymorphism Clinically Important in Polycystic Ovarian Syndrome (PCOS)? A Case-Control Study, Meta-Analysis and Trial Sequential Analysis. PLoS One.16;11(3):e0151510. doi: 10.1371
- 53. Singh K, Sinha P, Agrawal NK, Gupta SK, Singh K. (2016) Increased expression of TLR9 associated with pro-inflammatory S100A8 and IL-8 in diabetic wounds could lead to unresolved inflammation in type 2 diabetes mellitus (T2DM) cases with impaired wound healing. Journal of diabetes & its complications, 30;1:99-108.doi10.1016/j.jdiacomp.2015.10.002
- 52. Hasan MA, Kumari N, Singh K, Singh K, Mishra L. (2016) Mixed ligand complexes of Cu (II)/Zn (II) ions containing (m-)/(p-) carboxylato phenyl azo pentane 2, 4-dione and 2, 2'-bipyridine/1, 10 phenanthroline: Synthesis, characterization, DNA binding, nuclease and topoisomerase I inhibitory activity. SpectrochimicaActa Part
A: Molecular and Biomolecular Spectroscopy. 152; 208-217doi.org/10.1016/j.saa.2015.07.079
- 51. Jaiswal D, Trivedi S, Agrawal NK and Singh K. (2015) Dysregulation of apoptotic pathway candidate genes and proteins in infertile azoospermia patients. Fertility and Sterility, 104 (3), 736-743. e6doi.org/10.1016/j.fertnstert.2015.05.029
- 50. Singh K, Agrawal NK, Gupta SK, Mohan G, Chaturvedi S, Singh K. (2015) Genetic and Epigenetic alterations in Toll like Receptor 2 and wound healing impairment in type 2 diabetes patients. Journal of diabetes & its complications. 29 (2); 222-229doi.org/10.1016/j.jdiacomp.2014.11.015
- 49. Singh K, Agrawal NK, Gupta SK, Mohan G, Chaturvedi S, Singh K. (2015) Increased expression of endosomal members of Toll like Receptor family abrogates wound healing in Type 2 Diabetes Mellitus patients. International Wound Journal. doi: 10.1111/iwj.12411
- 48. Singh K, Agrawal NK, Gupta SK, Mohan G, Chaturvedi S, Singh K. (2015) Decreased expression of Heat Shock proteins may lead to compromised wound healing in type 2 diabetes mellitus patients. Journal of diabetes & its complications. 29 (4); 578-588doi.org/10.1016/j.jdiacomp.2015.01.007
- 47. Sinha P, Kumari N, Singh K, Singh K, Mishra L. (2015) Homolepticbisterpyridyl complexes: Synthesis, characterization, DNA binding, DNA cleavage and topoisomerase II inhibition activity. InorganicaChimicaActa. 432; 71-80doi.org/10.1016/j.ica.2015.03.026
- 46. Rai A, Kumari N, Nair R, Singh K and Mishra L. (2015) New rhodamine derivative as a single optical probe for the recognition of Cu2+ and Zn2+ ions. RSC Adv. 5: 14382-14388.doi10.1039/C4RA13332C
- 45. Nair RR, Khanna A, Singh K. (2015) Reduced myeloid-derived suppressor cells in the blood and endometrium is associated with early miscarriage. American Journal of Reproductive Immunology, 73(6):479-86.doi.org/10.1111/aji.12351
- 44. Jaiswal D, Trivedi S, Agrawal NK, Singh K. (2015) Association of the patterns of global DNA methylation and expression analysis of DNA methyltransferases in impaired spermatogenic patients, Asian Pacific Journal of Reproduction, http://dx.
DOI: 10.1016/j.apjr.2015.07.003}
- 43. Jaiswal D, Trivedi S, Agrawal NK, Singh K. (2015). Association of polymorphism in cell death pathway gene FASLG with human male infertility. Asian Pacific Journal of Reproduction, 4(2):112-115.
- 42. Singh Kand Singh K. (2015) Carcinogenesis and Diabetic wound healing: Evidences of parallelism. Current Diabetes Reviews. 11(1): 32-45.DOI: 10.2174/1573399811666150109122205
- 41. Singh S, Singh K and Sachan M (2015) Association study of functional polymorphisms of DNMT3A and DNMT3B genes with breast carcinoma in north Indian population. South Asian Journal of Experimental Biology, 5 (4): 121-126.
- 40. Agrawal S, Khanna A, Singh K. Agrawal A. (2015) Microdeletion of Y chromosome as a cause of recurrent pregnancy loss. Journal of Human Reproductive Sciences, doi:10.4103/0974 1208.165145.
- 39. Nair RR, Khanna A, Singh K. (2014) Association of Increased S100A8 Serum Protein with Early Pregnancy Loss. American Journal of Reproductive Immunology. doi: 10.1111/aji.12318.
- 38. Jaiswal D, Singh V, Dwivedi US, Trivedi S, Singh K. (2014) Chromosome microarray analysis: a case report of infertile brothers with CATSPER gene deletion. Gene, 542 (2): 263-5DOI: 10.1016/j.gene.2014.03.055
- 37. Jaiswal D, Trivedi S, Agrawal NK, Singh K. (2014) Association of the gonadotrophin-regulated testicular RNA helicase gene polymorphism with human male infertility. Andrologia, 46 (9), 1063-1066.
- 36. Jaiswal D, Trivedi S, Agrawal NK, Singh K. (2014) Chromosomal anomalies screening in the workup of male infertility in Northern Region of India. Indian Journal of Science, 12(32), 6-10.
- 35. Nair RR, Khanna A, Singh K. (2014) Association of Interleukin 1 Receptor Antagonist (IL-1RN) Gene polymorphism with recurrent pregnancy loss risk in the North Indian Population and a Meta-Analysis. Molecular Biology Reports, 41(9): 5719-5727.DOI: 10.1007/s11033-014-3443-8
- 34. Nair RR, Khanna A, Singh K. (2013) Association of Interleukin 1 beta (IL-1B) gene polymorphism with early pregnancy loss risk in the North Indian population.
International Journal of Immunogenetics, 41 (1), 41-43.DOI: 10.1111/iji.12044}
- 33. Singh K, Sri Kant, Singh VK, Agrawal NK, Gupta SK, Singh K. (2014) Toll-Like Receptor 4 polymorphisms and their haplotypes modulate the risk of developing diabetic retinopathy in type 2 diabetes patients. Molecular vision. 20: 704�713.
- 32. Singh K, Agrawal NK, Gupta SK, Mohan G, Chaturvedi S, Singh K. (2014) Differential expression of Matrix metalloproteinase-9 gene in wounds of T2DM cases with susceptible -1562C>T genotypes and wound severity.International journal of Lower Extremity Wounds. 13(2): 94 �102.
DOI: 10.1177/1534734614534980
- 31. Singh K, Singh VK, Agrawal NK, Gupta SK, Singh K. (2014) Genetic alterations in Toll like receptor 4 signalling pathway and impairment of wound healing in Type 2 diabetes patients. International journal of Lower Extremity Wounds. 13(2):162-163.DOI: 10.1177/1534734614529654
- 30. Singh K, Agrawal NK, Gupta SK, Singh K. (2014) Meta-analysis of variant rs 7903146 of TCF7L2 with secondary complications of Type 2 Diabetes Mellitus. Journal of Applied Biology & Biotechnology. 2(05): 001-005.
- 29. Singh K, Singh VK, Agrawal NK, Gupta SK, Singh K. (2013) Association of Toll-Like Receptor 4 polymorphisms with Diabetic Foot Ulcers and application of Artificial Neural Network in the assessment of DFU risk in Type 2 diabetes patients. Bio Med Research International, Volume 2013, Article ID 318686, 9 pages.DOI: 10.1155/2013/318686
- 28. Singh K, Agrawal NK, Gupta SK, Singh K. (2013) Association of Variant rs7903146 (C/T) Single Nucleotide Polymorphism of TCF7L2 Gene With Impairment in Wound Healing Among North Indian Type 2 Diabetes Population: A Case�Control Study. International journal of Lower Extremity Wounds. 12 (4): 310-315DOI: 10.1177/1534734613504435
- 27. Kanhaiya, Agrawal NK, Gupta SK, Singh K. (2013) Differential expression of Toll like Receptor 4 in Type 2 Diabetic patients with impaired wound healing. JournalofDiabetesandMetabolism, 4: 260.DOI: 10.4172/2155-6156.1000260}
- 26. Singh K, Agrawal NK, Gupta SK, Singh K. (2013) A Functional SNP-1562C>T in the Matrix Metalloproteinases-9 Promoter is associated with type 2 diabetes and Diabetic Foot Ulcers. International journal of Lower Extremity Wounds. 12(3):199-204DOI: 10.1177/1534734613493289
- 25. Nair RR, Khanna A, Singh R, Singh K. (2013) Association of Maternal and Fetal MTHFR A1298C polymorphism with the risk of pregnancy loss - A Study on an Indian Population and a Meta-Analysis. Fertility and Sterlity. 99 (5): 1311-1318.e4. DOI: 10.1016/j.fertnstert.2012.12.027
- 24. Nair RR, Khanna A, Singh K. (2013) Role of inflammatory proteins S100A8 and S100A9 in pathophysiology of recurrent early pregnancy loss. Placenta. 34 (9): 824�827. DOI: 10.1016/j.placenta.2013.06.307
- 23. Nair RR, Khanna A, Singh K. (2013) Association of GSTT1 and GSTM1 polymorphisms with early pregnancy loss in an Indian population and a meta-analysis. Reproductive Biomedicine Online, 26:313-322.DOI 10.1016/j.rbmo.2012.12.004
- 22. Sachan S, Nair R R, Khanna A, Singh K. (2013) CYP1A1 and GSTM1 genes polymorphism and its association with endometriosis: A pilot study. Asian Pacific Journal of Reproduction,2: 297�300.DOI: 10.1016/S2305-0500(13)60165-7}
- 21. Nair RR, Khanna A, Singh K. (2013) CBS 844ins68 and ms d919g polymorphism: early pregnancy loss risk. International Journal of Bioassay, 2: 503-505.
- 20. Jaiswal D, Trivedi S, Agrawal NK, Singh R, Singh K (2013) Association of Interleukin-1beta C+3953T gene polymorphism with human male infertility. System biology reproductive medicine. 59, (6): 347-351.DOI: 10.3109/19396368.2013.830234
- 19. Roy S, Matah M, Jaiswal D, Singh K. Role of- 460 C/T VEGF gene polymorphism in preeclampsia. Asian Pacific Journal of Reproduction. 2013 Mar 1;2(1):30-3. Doi:10.1016/S2305-0500(13)60111-6
- 18. Agrawal NK, Prakash V, Singh K. Saving the bones in breast cancer: aromatase inhibitor-induced osteoporosis. Expert Review of Endocrinology & Metabolism. 2013 Jul 1;8(4):311-3. Doi:10.1586/17446651.2013.811892
- 17. Singh K, Jaiswal D. One-carbon metabolism, spermatogenesis, and male infertility. Reproductive Sciences. 2013 Jun;20(6):622-30. doi: 10.1177/1933719112459232.
- 16. Jaiswal D, Trivedi S, Singh R, Dada R, Singh K. Association of the IL1RN gene VNTR polymorphism with human male infertility. PloS one. 2012 Dec 14;7(12):e51899.Doi: 10.1371/journal.pone.0051899
- 15. Jaiswal D, Sah R, Agrawal NK, Dwivedi US, Trivedi S, Singh K. Combined effect of GSTT1 and GSTM1 polymorphisms on human male infertility in north Indian population. Reproductive Sciences. 2012 Mar;19(3):312-6. Doi:10.1177/1933719111424451
- 14. Jaiswal D, Dwivedi US, Agrawal NK, Trivedi S, Singh K. FAS-670 A/G and FAS-1377 G/A polymorphism in cell death pathway gene FAS and human male infertility. Asian Pacific Journal of Reproduction. 2012 Sep 1;1(3):183-6.DOI: 10.1016/S2305-0500(13)60074-3.
- 13. Nair RR, Khanna A, Singh K. MTHFR C677T polymorphism and recurrent early pregnancy loss risk in north Indian population. Reproductive Sciences. 2012 Feb;19(2):210-5.DOI: 10.1177/1933719111417888
- 12. Nair RR, Khanna A, Singh K. Association of FAS- 1377 G> A and FAS- 670 A> G functional polymorphisms of FAS gene of cell death pathway with recurrent early pregnancy loss risk. Journal of reproductive immunology. 2012 Mar 1;93(2):114-8.doi:10.1016/j.jri.2011.12.004
- 11. Singh K, Nair R. R, Khanna A (2012), Functional SNP �1562C/T in the promoter region of MMP9 and recurrent early pregnancy loss, Reproductive BioMedicine Online, 24:61-65.doi:10.1016/j.rbmo.2011.09.007
- 10. Singh K, Jaiswal D. Human male infertility: a complex multifactorial phenotype. Reproductive Sciences. 2011 May;18(5):418-25.DOI: 10.1177/1933719111398148
- 9. Nair RR, Jain M, Singh K. Reduced expression of gap junction gene connexin 43 in recurrent early pregnancy loss patients. Placenta. 2011 Aug 1;32(8):619-21.doi:10.1016/j.placenta.2011.05.010
- 8. Singh K, Singh SK, Raman R. MTHFR A1298C polymorphism and idiopathic male infertility. Journal of postgraduate medicine. 2010 Oct 1;56(4):267. Doi: N/A
- 7. Singh K, Singh S.K, Raman R. (2010) MTHFR A1298C polymorphism and idiopathic male infertility. Journal of Postgraduate Medicine (JPGM), 56 (4): 267-269.
- 6. Singh K, Raman R, (2009) A386G polymorphism of the DAZL gene is not associated with idiopathic male infertility in North India. Journal of Human Reproductive Sciences, 2 (2):53-55.
- 5. Singh K, Agrawal N K, Khanna A, Jain M, Pandey S (2009) Cystathionine �-Synthase 844ins68 Gene Variant and idiopathic Male infertility. Reproductive Sciences, Online, DOI: 10.1177/1933719109341844.
- 4. Singh K and Raman R (2009) Y-haplotypes and idiopathic male infertility in an Indian population. Indian Journal of Human Genetics, 15:19-22.
- 3. Singh K., Singh S.K., Sah R., Singh I, Raman R (2005) Mutation C677T in the methylenetetrahydrofolate reductase gene is associated with male infertility in an Indian population. International Journal of Andrology, 28 (2): 115-119.
- 2. Singh K and Raman R (2005) Male Infertility: Y-chromosome deletions and testicular etiology in cases of azoo-/oligospermia. Indian Journal of Experimental Biology, 43: 1088-1092.
- 1. Ambasudhan R., Singh K., Agarwal J.K., Singh S.K., Khanna A., Sah R., Singh I., Raman R. (2003) Idiopathic cases of male infertility from a region in India show low incidence of Y-chromosome microdeletion. Journal of Biosciences, 28: 605-612.
B. Books:
- (Springer Publication, ISBN No: 978-981-10-4016-0 , ISBN 978-981-10-4017-7 (eBook), DOI 10.1007/978-981-10-4017-7� Springer)
Title: Male Infertility: Understanding, causes and treatment.
Editors: Dr. Kiran Singh, Asstt. Professor, Dept. of Molecular & Human Genetics,
Banaras Hindu Univesity, Varanasi-221005.
Dr. Rajender Singh, Senior Scientist, Central Drug Research Institute, Lucknow.
- Intech Open, ISBN No: 978-953-51-3811-2, DOI 10.5772/intechopen.68300)
Title: Debatable Topics in PCOS Patients
Editors: Dr. Kiran Singh, Asst. Professor, Dept. of Molecular & Human Genetics,
Banaras Hindu University, Varanasi-221005.
Prof. Neeraj Kumar Agarwal, Prof and the Head of the Department of Endocrinology and Metabolism,
Institute of Medical Sciences, Banaras Hindu University, Varanasi-221005.
- Editor of the 19th issue of ISSRF (Indian Society for Study in Reproduction & Fertility) Newsletter (ISSN No. 2395-2806), September 2016.
C. Book Chapter:
- 1.Singh K. (2009) Prenatal diagnosis of common genetic disorders in Women Mental Health, Sharma, I and Tripathi, M N (Eds), Indian Psychiatric Society Publication, Pp 39-50.
- 2. Singh K and Nair R.R (2014) Genetic Polymorphisms and Molecular Pathogenesis of Early pregnancy loss in book entitled Trends in Reproductive Biology & Endocrinology, ISBN: 978-93-819793-7-2, CBH Publishers & Distributors, Bengaluru, India
- 3. Singh K and Raman R, (2015) Genomics of Male Infertility in book entitled Mammalian Endocrinology and Male Reproductive Biology, ISBN: 978-1498727358, CRC Press, Premier global publisher, Pp 299-318.
- 4. Verma, P., & Singh, K. (2017). Homoplasy. In Encyclopedia of Animal Cognition and Behavior Springer International Publishing. ISBN No: 978-3-319-47829-6 (eBook), DOI 10.1007/978-3-319-47829-6.
- 5. Budhwar S & Singh K. (2017). Hybrid Vigor. In Encyclopedia of Animal Cognition and Behavior Springer International Publishing. ISBN No: 978-3-319-47829-6 (eBook), DOI 10.1007/978-3-319-47829-6.
- 6. Bala R., & Singh K. (2017) Green Beard. In Encyclopedia of Animal Cognition and Behavior (pp. 1-3). Springer International Publishing.ISBN No: 978-3-319-47829-6 (eBook), DOI 10.1007/978-3-319-47829-6
- 7. Singh V, Agarwal NK, Verma R, Singh K (2017) HPG Axis: The Central Regulator of Spermatogenesis and Male Fertility in book entitled Male Infertility: Understanding, causes and treatment Springer Publication, ISBN No: 978-981-10-4016-0, ISBN 978-981-10-4017-7 (eBook), DOI 10.1007/978-981-10-4017-7� Springer.
- 8. Singh V, Singh K (2017) Genomic Landscape of Human Y Chromosome and Male Infertility in book entitled Male Infertility: Understanding, causes and treatment Springer Publication, ISBN No: 978-981-10-4016-0, ISBN 978-981-10-4017-7 (eBook), DOI 10.1007/978-981-10-4017-7� Springer.
- 9. Singh V, Singh R, Singh K (2017) Syndromic forms of male infertility in book entitled Male Infertility: Understanding, causes and treatment Springer Publication, ISBN No: 978-981-10-4016-0, ISBN 978-981-10-4017-7 (eBook), DOI 10.1007/978-981-10-4017-7� Springer.
- Singh V, Singh K (2017) Cytogenetic factors in Male Infertility in book entitled Male Infertility: Understanding, causes and treatment Springer Publication, ISBN No: 978-981-10-4016-0 , ISBN 978-981-10-4017-7 (eBook), DOI 10.1007/978-981-10-4017-7� Springer.
- Singh V, Singh R, Kumar BS, Singh K (2017) Autosomal Genes in male infertility in book entitled Male Infertility: Understanding, causes and treatment Springer Publication, ISBN No: 978-981-10-4016-0 , ISBN 978-981-10-4017-7 (eBook), DOI 10.1007/978-981-10-4017-7� Springer.
- Kumar BS, Singh K Singh V, Singh R (2017) Sex chromosomal Genes in male infertility in book entitled Male Infertility: Understanding, causes and treatment Springer Publication, ISBN No: 978-981-10-4016-0, ISBN 978-981-10-4017-7 (eBook), DOI 10.1007/978-981-10-4017-7� Springer.
- Singh V & Singh K. (2018). Modern Synthesis. In Encyclopedia of Animal Cognition and Behavior (pp. 1-3). Springer International Publishing. ISBN No: 978-3-319-47829-6 (eBook), DOI 10.1007/978-3-319-47829-6.
- Singh V & Singh K. (2018). Indirect Association. In Encyclopedia of Animal Cognition and Behavior Springer International Publishing. ISBN No: 978-3-319-47829-6 (eBook), DOI 10.1007/978-3-319-47829-6.
- Singh V & Singh K. (2018). Additive Genetic Variance. In Encyclopedia of Animal Cognition and Behavior Springer International Publishing. ISBN No: 978-3-319-47829-6 (eBook), DOI 10.1007/978-3-319-47829-6.
D. Presentations in meetings and symposia (with published abstracts):
- Jaiswal D , Agrawal N.K, Trivedi S, Singh K (2011) Polymorphism of Cell Death Pathway Gene variant in Human Male Infertility, 36th Annual conference of Indian Society of Human Genetics (ISHG), Manipal Life Sciences Centre, Manipal University, Manipal, India.
- Nair R, Jaiswal D, Pandey P, Jain M, Singh K (2011) C677T MTHFR variation in Indian women with polycystic ovary syndrome and its association with clinical & biochemical parameters, 36th Annual conference of Indian Society of Human Genetics (ISHG), Manipal Life Sciences Centre, Manipal University, Manipal, India.
- Kanhaiya, Nair R, Sachan S, Khanna A, Singh K (2011) Polymorphism in detoxification pathway genes (CYP1A1, GSTM1 and GSTT1) and Dysmenorrhea in North Indian women, 36th Annual conference of Indian Society of Human Genetics (ISHG), Manipal Life Sciences Centre, Manipal University, Manipal, India.
- Nair R, Khanna A, Singh K (2010) Cytochrome P450 1A1 (CYP1A1) T6235C polymorphism and polycystic ovary syndrome risk in North Indian population, XXIV All India Cell Biology Conference (AICBC2010), Bose Institute, Kolkata.
- Jaiswal D, Singh K (2010) Molecular and cytogenetic analysis of idiopathic human male infertility, XXIV All India Cell Biology Conference (AICBC2010), Bose Institute, Kolkata.
- Kanhaiya, Sri Kant, Singh K (2010) Functional SNP -1562 C/T polymorphism in the Matrix metalloproteinase-9 promotor as a potential risk factor risk factor for proliferative diabetic retinopathy. XXIV All India Cell Biology Conference (AICBC2010), Bose Institute, Kolkata.
- Pandey P, Jain M, Singh K (2010) Study of CYP1A1 gene polymorphisms in PCOS patients in North Indian population, Federation of Gynae, Society of India, 2010, Gorakhpur.
- Botra A, Paul D, Singh N, Poundel S, Raj S, Singh K (2010) Cytogenetic Analysis of Human Genetics Disorders, 35th Indian Society of Human Genetics Conference, 2010, SGPGI, Lucknow.
- Raman R, Rai A, Singh K, (2006) 1-carbon metabolism pathway genes in human diseases. Indo-US symposium on genetic disorders: Focus on Hemoglobinopathies, Banaras Hindu University, Varanasi, India
- Singh Kiran, Raman R. (2006) International symposium on Environmental factors, cellular stress and evolution, Banaras Hindu University, Varanasi, India
- Singh K, Raman R. (2006) Polymorphisms in 1-Carbon Metabolism Genes and Susceptibility to Human Diseases. International symposium on � Human Genomics and Public Health� XXXI Annual conference of Indian society of human genetics Jawaharlal Nehru University, New Delhi, India.
- Singh K, Raman R. (2006) Genetic risk factors affecting idiopathic male infertility in an Indian population. Indian society of Cell Biology XXIX Annual conference ITRC, Lucknow, India.
- Singh K and Raman R. (2005) Single nucleotide polymorphisms in the gene methyltetra-hydrofolate reductase and reproductive health: an Indian perspective. International symposium on advances and challenges in reproductive health research In the post genomic era. National Institute for Research in Reproductive Health, Mumbai, India.
- Singh K, Raman R. (2004) C677T MTHFR gene mutation is a risk factor for male infertility in Indian population. Indian society of Cell Biology XXVIII Annual conference Panjab University, Chandigarh, India.
- Singh K and Raman R. (2004) Genomics of male infertility.14th annual meeting of the Indian Society for the Study of Reproduction and Fertility (ISSRF), IISc, Bangalore, India.
- Singh K, Rajesh .A, Singh S.K, Sah R, Singh I, Raman R. (2002) Cytogenetic And molecular studies of the human Y-chromosome in idiopathic in idiopathic infertility. Indian society of Cell Biology XXVI Annual conference ACTREC, Mumbai, India.
- Singh K and Raman R. (2001) Presence of SRY and ZFY genes in cytogenetically XX infant suffering from congenital adrenal hyperplasia. Indian society of Cell Biology XXV Annual conference IISc Bangalore, India.
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