Institute of Science comprises thirteen Departments covering almost all the branches in modern science. It offers B.Sc.(Hons.) and M.Sc. courses in most disciplines, M.Sc. (Tech.) in Geophysics, MCA, and conducts research programmes in all areas. Two vocational courses, Industrial Microbiology and Electronics Instrumentation and Maintenance have been introduced in recent years at U.G. level. The Departments have expertises in various related fields and are engaged in advanced research activities. The School of Biotechnology has introduced a new course on Cell Biology and Virology. It has a Bioinformatics User Center. The Department of Chemistry has been conducting research in the frontier areas of subject like Nuclear and Radio Chemistry, Organometillic Chemistry, Biosensor. The Department of Geography has a new course of Satellite Imagery Interpretation. The Department of Geology is a pioneering department in the country. The Department of Mathematics has thrust areas of research in relativity, fluid mechanics and operations research. The Department of Physics, a leading Department in the country, has International Collaboration Programmes like Indo-German and Indo-US. The Department of Statistics has two major research projects sponsored by Rockefeller Foundation. The Departments of Statistics & Botany have introduced Self-financing courses in Population Studies and Environmental Science respectively. Department of Computer Science runs B.Sc. and M.Sc. courses. Home Science is taught at MMV. Department of Biochemistry has postgraduate teaching and research programmes.

The Departments of Botany, Zoology, Physics, Geology and Chemistry are recognized Centers of Excellence and Centers of Advanced Study. The Department of Geophysics receives grants under Special Assistance Programme. The Institute of Science keeps itself alive with regular academic activities like seminars, workshops, conferences. It is equipped with advanced and sophisticated laboratories. Faculty members have liaison with research institutions of repute in India and abroad. A large number of the teachers of the Institute have received distinctions and honors like Shanti Swarup Bhatnagar Prize, Jawaharlal Nehru Fellowship, FICCI Award, etc. and several are fellows of the various academies.